GPR179 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) GPR179 Polyclonal antibody
Uniprot No.：

Q6PRD1
基因名：

GPR179
別名：

G protein coupled receptor 179 antibody; GP179_HUMAN antibody; GPR158 like 1 antibody; GPR158L1 antibody; GPR179 antibody; Probable G-protein coupled receptor 158-like 1 antibody; Probable G-protein coupled receptor 179 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Probable G-protein coupled receptor 179 protein (1440-1671AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Orphan receptor, involved in vision. Required for signal transduction through retinal depolarizing bipolar cells.
基因功能參考文獻：
1. In this study, a novel compound heterozygous mutation, c.[1A>G]; [608G>T] (p.[0?]; p.[W203L]), was identified in the LRIT3 gene of a proband. No mutations were identified in the CABP4 or GPR179 gene. PMID: 27428514
2. We found 1 mutation in GPR179 in congenital stationary night blindness. PMID: 23714322
3. Additional screening with Sanger sequencing of 40 patients identified three other cCSNB patients harboring additional allelic mutations in GPR179. PMID: 22325361
相關疾病：

Night blindness, congenital stationary, 1E (CSNB1E)
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 3 family
組織特異性：

Expressed in the retina.
數據庫鏈接：

HGNC: 31371

OMIM: 614515

KEGG: hsa:440435

STRING: 9606.ENSP00000345060

UniGene: Hs.462915

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