GPR158 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) GPR158 Polyclonal antibody
Uniprot No.：

Q5T848
基因名：

GPR158
別名：

5330427M13Rik antibody; GP158_HUMAN antibody; GPR158 antibody; mKIAA1136 antibody; Probable G-protein coupled receptor 158 antibody; RP11-59G22.1 antibody; RP23-133B16.1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Probable G-protein coupled receptor 158 protein (882-1003AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Orphan receptor.
基因功能參考文獻：
1. Our results suggest that common ethnic-specific variation in GPR158 may influence energy expenditure (EE) in Pima Indians. rs11014566 nominally associated with measures of EE and adiposity, where the G allele associated with lower 24-h EE, lower Resting Metabolic Rate, higher BMI, and higher percent body fat. But, the association of rs11014566 with BMI did not directionally replicate when assessed in other ethnic groups. PMID: 28476931
2. expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression PMID: 25693195
3. Mutation of the NLS abrogates GPR158-mediated enhancement of cell proliferation. PMID: 23451275
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 3 family
數據庫鏈接：

HGNC: 23689

OMIM: 614573

KEGG: hsa:57512

STRING: 9606.ENSP00000365529

UniGene: Hs.499108

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