GPR137 Antibody
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中文名稱：GPR137兔多克隆抗體
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貨號(hào)：CSB-PA009752GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：GPR137
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別名：GPR137; C11orf4; GPR137A; TM7SF1L1; Integral membrane protein GPR137; Transmembrane 7 superfamily member 1-like 1 protein
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human GPR137
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy.; May activate Wnt/beta-catenin signaling to modulate epithelial cell function.
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基因功能參考文獻(xiàn)：
- High GRP137 expression is associated with metastasis in ovarian cancer. PMID: 29739299
- findings imply that GPR137 plays an important role in the occurrence and progression of PCa and may prove to be a potential therapeutic target for the treatment of advanced PCa PMID: 26669804
- GPR137 as an essential player in urinary bladder cancer cell growth PMID: 25496438
- GPR137 knockdown inhibited growth of Daoy medulloblastoma cells via disturbing cell cycle progression and inducing apoptosis PMID: 25524330
- GPR137 as a potential oncogene in pancreatic cancer cells PMID: 25471990
- Knockdown of GPR137 in HepG2 cells led to cell cycle arrest at G0/G1 phase and G2/M phase, and induced cell apoptosis, as determined by flow cytometry analysis, which contributed to cell growth inhibition. PMID: 25490967
- Our results indicated that GPR137 is involved in the progression of human glioma PMID: 24870220
- Expression levels of GRP137 were analyzed in different colon cancer cell lines. Silencing of GPR137 reduced the proliferation rate and colony numbers. PMID: 25301753
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亞細(xì)胞定位：Lysosome membrane; Multi-pass membrane protein.
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蛋白家族：GPR137 family
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數(shù)據(jù)庫鏈接：
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