GPR133 Antibody

產(chǎn)品詳情

Uniprot No.：

Q6QNK2
基因名：

ADGRD1
別名：

DKFZp434B1272 antibody; FLJ16770 antibody; G protein coupled receptor 133 antibody; G protein coupled receptor PGR25 antibody; G-protein coupled receptor PGR25 antibody; GP133_HUMAN antibody; Gpr133 antibody; MGC138512 antibody; MGC138514 antibody; PGR25 antibody; Probable G-protein coupled receptor 133 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Monkey
免疫原：

Synthesized peptide derived from the Internal region of Human GPR133.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, IF, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

平均分:

5.0分 - 1 個(gè)評(píng)價(jià)

實(shí)驗(yàn)應(yīng)用：WB

樣品信息：細(xì)胞裂解液

稀釋比：1:1000

產(chǎn)品評(píng)價(jià)：我使用CSB-PA008902抗體進(jìn)行細(xì)胞中GPR133蛋白表達(dá)的WB檢測(cè)，因?yàn)槭悄さ鞍姿杂玫?7℃，30min變性蛋白。上樣量為15ug總蛋白，條帶很清晰，結(jié)果還算不錯(cuò)。

By 劉老師

功能：

Orphan receptor. Signals via G(s)-alpha family of G-proteins. Has protumorigenic function especially in glioblastoma.
基因功能參考文獻(xiàn)：
1. The results show that a broad spectrum of functionally relevant ADGRD1 variants is present in the human population which may cause clinically relevant phenotypes, while being compatible with life when heterozygous. PMID: 27516204
2. Cell adhesion receptor GPR133 couples to Gs protein PMID: 22025619
3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
4. A role for GPR133 protein in affecting the length of the electrocardiographic RR interval and heart rate. PMID: 20031603
5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20031603
6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19729412
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亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
組織特異性：

Up-regulated in CD133(+) cell population of glioblastoma.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 19893

OMIM: 613639

KEGG: hsa:283383

STRING: 9606.ENSP00000261654

UniGene: Hs.719239

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