GPC5 Antibody
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中文名稱：GPC5兔多克隆抗體
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貨號：CSB-PA009707GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：GPC5
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別名：bA93M14.1 antibody; glypican 5 antibody; Glypican 5 precursor antibody; glypican proteoglycan 5 antibody; Glypican-5 antibody; GPC5 antibody; GPC5_HUMAN antibody; Secreted glypican-5 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human GPC5
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Cell surface proteoglycan that bears heparan sulfate.
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基因功能參考文獻：
- Our results showed that GPC5 was lowly expressed in PCa cell lines. PMID: 28893348
- Taken together, our results suggest GPC5 as a tumor suppressor in PDAC and its expression is possibly regulated by miR-4295. Our study indicates that the miR-4295/GPC5 axis may play an important role in the pathogenesis of PADC and has potential applications for the development of PDAC therapy. PMID: 29407175
- Suggest that GPC5 is able to suppress the lung adenocarcinoma metastasis by competitively binding to Wnt3a and inactivating the Wnt/beta-catenin signaling pathway. PMID: 27806326
- GPC5 is a novel epigenetically silenced tumor suppressor, which inhibits tumor growth by suppressing Wnt/beta-catenin signaling in lung adenocarcinoma. PMID: 27157618
- GPC5 protein expression showed a close correlation with the tumorigenesis and tumor progression of prostate cancer, and that might be applied as a novel biomarker for the prediction of diagnosis and prognosis of prostate cancer. PMID: 26631038
- These results suggest that miR-297 acted as an oncogenic miRNA, partly by targeting GPC5, adenocarcinoma of the lung. PMID: 27554041
- Results suggest a potential association between CRP and GPC5 variants with lung cancer risk; variation in GKN1 is associated with chemotherapy response in the Chinese Han population. PMID: 25999661
- miR-709 may positively regulate invasion and metastasis of hepatocellular carcinoma through targeting GPC5. PMID: 25818666
- gene variants in IRF5, IRF8 and GPC5 were not associated with risk of relapse or disease progression in multiple sclerosis PMID: 24943672
- GPC5, a tumor suppressor, is regulated by miR-620 in lung adenocarcinoma. PMID: 24682381
- Variants in the 50-upstream region of GPC5 confer risk of lung cancer in never smokers PMID: 24456789
- These results indicate that GPC5 polymorphisms would be useful genetic indicators for Inflammatory demyelinating diseasess, including neuromyelitis optica and multiple sclerosis . PMID: 24135429
- The IL7R, TNFRSF1A, and GPC5 polymorphisms tended to be associated with having a second event of Multiple sclerosis within a year. PMID: 24130709
- Shh binds to HSPG co-receptors containing a glypican 5 core and 2-O-sulfo-iduronic acid to promote neural precursor proliferation. PMID: 23867465
- Data suggest that glypican-5 (GPC5) is a metastasis suppressor gene in non-small cell lung cancer (NSCLC) and may be a potential biomarker that predicts NSCLC metastasis. PMID: 23962560
- GPC5 is a gene required for normal neural tube development. PMID: 23223018
- findings suggested that SNP rs2352028 in GPC5 might confer a slight risk to lung cancer/adenocarcinoma PMID: 22236185
- GPC5 stimulates Hh signaling by facilitating/stabilizing the interaction between Hh and Ptc1. PMID: 21339334
- GPC5 is a novel genetic locus protective against sudden cardiac arrest PMID: 20360844
- This study supports that multiple sclerosis susceptibility at 13q31-32 may localize to the Glypican-5 gene. PMID: 20692050
- No association between GPC5rs2352028 variant and lung cancer in never smokers in meta-analysis of 7 genome-wide association studies under the random effects model. PMID: 20688270
- GPC5 polymorphism associated with susceptibility to lung cancer in never smokers PMID: 20304703
- GPC5 is a possible target for the 13q31-q32 amplification detected in lymphoma cell lines. PMID: 12721791
- Independent replication confirms GPC5 as a genetic risk factor for multiple sclerosis. PMID: 19010793
- ZIC2, SPRY2, and GPC5 genes are candidate genes suspected to explain the malformations associated with cerebral anomalies in the hypothesis of a contiguous gene syndrome in 13q deletion syndrome PMID: 19022413
- Confirm the association of polymorphisms within GPC5 with response to interferon-beta therapy in patients with multiple sclerosis. PMID: 19556317
- Genome-wide association study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 18195134
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亞細胞定位：Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.; [Secreted glypican-5]: Secreted, extracellular space.
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蛋白家族：Glypican family
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組織特異性：In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver.
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數據庫鏈接：
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