GNL2 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) GNL2 Polyclonal antibody
Uniprot No.：

Q13823
基因名：

GNL2
別名：

Autoantigen NGP-1 antibody; Autoantigen NGP1 antibody; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein antibody; FLJ40906 antibody; GNL2 antibody; Guanine nucleotide binding protein-like 2 (nucleolar) antibody; HUMAUANTIG antibody; NGP1 antibody; NOG2_HUMAN antibody; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen antibody; nucleolar G-protein gene 1 antibody; Nucleolar GTP binding protein 2 antibody; Nucleolar GTP-binding protein 2 antibody; Nucleolar GTPase antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Nucleolar GTP-binding protein 2 protein (1-731AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，GNL2 Antibody (CSB-PA618806LA01HU)，的標記方式是Non-conjugated。對于GNL2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA618806LB01HU	GNL2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA618806LC01HU	GNL2 Antibody, FITC conjugated
Biotin	CSB-PA618806LD01HU	GNL2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
基因功能參考文獻：
1. NGP-1 promotes cell cycle progression through the activation of the p53/p21(Cip-1/Waf1) pathway. PMID: 26203195
2. GNL2 and SEC13 are required for nonsense-mediated mRNA decay pathway in human cells. PMID: 25452588
亞細胞定位：

Nucleus, nucleolus.
蛋白家族：

TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily
組織特異性：

Widely expressed, with the highest expression level in testis.
數據庫鏈接：

HGNC: 29925

OMIM: 609365

KEGG: hsa:29889

STRING: 9606.ENSP00000362153

UniGene: Hs.75528

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