GNAS Antibody

中文名稱：

GNAS兔多克隆抗體
貨號：

CSB-PA352389LA01HU
規格：

￥440
圖片：
Western Blot
Positive WB detected in: Rat brain tissue, Mouse brain tissue
All lanes: GNAS antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46, 45, 112, 110, 78, 29 kDa
Observed band size: 46 kDa

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA352389LA01HU at dilution of 1:100

Immunofluorescent analysis of MCF-7 cells using CSB-PA352389LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品描述：

The GNAS antibody is generated by immunizing rabbits with the full-length amino acids of the human GNAS protein. It is a polyclonal antibody and occurs as an unconjugated IgG. Its purity is greater than 95% using protein G purified. It shows cross-reactivity with human, mouse, and rat GNAS protein. This GNAS antibody is available for use in ELISA, WB, IHC, and IF applications. The target protein GNAS is the stimulatory alpha subunit of the guanine nucleotide-binding protein (G protein), which is a widely expressed signaling protein essential for the actions of many hormones and other endogenous molecules.
產品名稱：

Rabbit anti-Homo sapiens (Human) GNAS Polyclonal antibody
Uniprot No.：

P63092
基因名：

GNAS
別名：

Adenylate cyclase-stimulating G alpha protein antibody; AHO antibody; alternative gene product encoded by XL-exon antibody; C20orf45 antibody; extra large alphas protein antibody; GNAS antibody; GNAS complex locus antibody; GNAS1 antibody; GNAS1 gene, formerly antibody; GNAS1, formerly antibody; GNAS2_HUMAN antibody; GPSA antibody; GSA antibody; GSP antibody; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody; guanine nucleotide regulatory protein antibody; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short antibody; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas antibody; NESP antibody; neuroendocrine secretory protein antibody; PHP1A antibody; PHP1B antibody; PHP1C antibody; POH antibody; protein ALEX antibody; secretogranin VI antibody
宿主：

Rabbit
反應種屬：

Human, Mouse, Rat
免疫原：

Recombinant Human Guanine nucleotide-binding protein G(s) subunit alpha isoforms short protein (1-394AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，GNAS Antibody (CSB-PA352389LA01HU)，的標記方式是Non-conjugated。對于GNAS Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA352389LB01HU	GNAS Antibody, HRP conjugated	ELISA
FITC	CSB-PA352389LC01HU	GNAS Antibody, FITC conjugated
Biotin	CSB-PA352389LD01HU	GNAS Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.
相關疾病：

Albright hereditary osteodystrophy (AHO); Pseudohypoparathyroidism 1A (PHP1A); McCune-Albright syndrome (MAS); Progressive osseous heteroplasia (POH); ACTH-independent macronodular adrenal hyperplasia 1 (AIMAH1); Pseudohypoparathyroidism 1B (PHP1B); GNAS hyperfunction (GNASHYP); Pseudohypoparathyroidism 1C (PHP1C)
亞細胞定位：

Cell membrane; Lipid-anchor.
蛋白家族：

G-alpha family, G(s) subfamily
數據庫鏈接：

HGNC: 4392

OMIM: 103580

KEGG: hsa:2778

UniGene: Hs.125898

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