GK Antibody, FITC conjugated

說明書

中文名稱：

GK兔多克隆抗體, FITC偶聯
貨號：

CSB-PA300097LC01HU
規格：

￥880
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) GK Polyclonal antibody
Uniprot No.：

P32189
基因名：

GK
別名：

ATP glycerol 3 phosphotransferase antibody; ATP:glycerol 3 phosphotransferase antibody; ATP:glycerol 3-phosphotransferase antibody; D930012N15Rik antibody; GK antibody; GK1 antibody; GKD antibody; GLPK_HUMAN antibody; Glycerokinase antibody; Glycerol kinase antibody; OTTHUMP00000023108 antibody; OTTHUMP00000023109 antibody; OTTHUMP00000215321 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Glycerol kinase protein (346-509AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Key enzyme in the regulation of glycerol uptake and metabolism.
基因功能參考文獻：
1. Both patients were found to have Xp21.2 deletions involving all coding seqeunces of the glycerol kinase (GK) gene. PMID: 27087023
2. Two siblings with the contiguous X-linked gene deletion syndrome, complex glycerol kinase deficiency, are described. The elder sibling demonstrates the difficulties diagnosing this rare condition. PMID: 20110216
3. missense mutations and deletions in glycerol kinase is associated with persistent hypertriglyceridemia PMID: 12636049
4. a functional HNF-4alpha binding site in the first 500 bp of the 5(') upstream region is important for increased levels of glycerol kinase expression PMID: 14654354
5. Comparison of expression patterns, as well as enzymatic characteristics and subcellular localization of alternatively spliced glycerol kinase isoforms. PMID: 15845384
6. Results suggest that influences on RNA processing and protein stability represent modifiers of the glycerol kinase deficiency phenotype. PMID: 16549535
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相關疾病：

Glycerol kinase deficiency (GKD)
亞細胞定位：

Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.
蛋白家族：

FGGY kinase family
組織特異性：

Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.
數據庫鏈接：

HGNC: 4289

OMIM: 300474

KEGG: hsa:2710

UniGene: Hs.1466

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