GINS2 Antibody
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中文名稱：GINS2兔多克隆抗體
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貨號：CSB-PA009431GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：GINS2
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別名：DNA replication complex GINS protein PSF2 antibody; GINS complex subunit 2 (Psf2 homolog) antibody; GINS complex subunit 2 antibody; gins2 antibody; HSPC037 antibody; Pfs2 antibody; PSF2 antibody; PSF2_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human GINS2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
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基因功能參考文獻：
- The authors show that GINS is a compact tetramer in solution as observed in crystal structures, but also forms a double-tetrameric population, detectable by electron microscopy. PMID: 28071757
- GINS2 is overexpressed in cervical cancer.GINS2 is a novel indicator of pelvic lymph node metastasis in cervical cancer. PMID: 28405687
- silencing of GINS2 in triple negative breast cancer cells caused dramatic decrease of matrix metalloproteinase-9 (MMP9). PMID: 27829549
- High GINS2 transcript level is associated with endocrine therapy resistance in beast cancer. PMID: 25348432
- On the contrary, after HL60 cells were infected by recombinant adenovirus vector which contained GINS2 gene, we observed that over-expression of GINS2 could promote HL-60 cell proliferation. PMID: 24273454
- GINS2 plays an important role in apoptosis and may function via the p38MAPK signaling pathway. PMID: 23589040
- Data show that using a 200-nt primed circular DNA substrate, the combined action of DNA polymerase epsilon and the Cdc45/Mcm2-7/GINS (CMG complex) leads to the formation of products >10 kb in length. PMID: 22474384
- Data suggest that GINS2 to be associated with the aggressive characteristics of a subgroup of breast cancers in vivo. PMID: 21082043
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亞細胞定位：Nucleus. Chromosome.
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蛋白家族：GINS2/PSF2 family
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數據庫鏈接：
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