G0S2 Antibody, Biotin conjugated
-
中文名稱：G0S2兔多克隆抗體, Biotin偶聯
-
貨號：CSB-PA009114ED01HU
-
規格：￥880
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) G0S2 Polyclonal antibody
-
Uniprot No.：
-
基因名：G0S2
-
別名：G0/G1 switch regulatory protein 2 antibody; G0/G1switch 2 antibody; G0s2 antibody; G0S2_HUMAN antibody; OTTHUMP00000034644 antibody; Putative lymphocyte G0/G1 switch protein 2 antibody; RP1 28O10.2 antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human G0/G1 switch protein 2 protein (1-103AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Biotin
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：>95%, Protein G purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
-
應用范圍：ELISA
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
-
基因功能參考文獻：
- ER+ breast cancer cells with restored G0S2 expression had a relative increased sensitivity to tamoxifen PMID: 28910567
- Palmitate can induce lipid accumulation in HepG2 cells by activating C/EBPbeta-mediated G0S2 expression. PMID: 29209111
- G0S2 functions as a master regulator of tissue-specific balance of TG storage vs. mobilization, partitioning of metabolic fuels between adipose and liver, and the whole-body adaptive energy response. PMID: 28645852
- PML/RARalpha synergizes with C/EBPepsilon to reactivate the C/EBPepsilon target G0S2, thereby contributing to All-trans retinoic acid -mediated acute promyelocytic leukemia differentiation and potentially, clinical remission. PMID: 27605212
- differences in G0S2 expression may explain depot-specific and obesity-associated differences in lipolysis on the molecular level PMID: 26707160
- Data indicate that a tumor suppressor mechanism by which G0/G1 switch gene 2 product (G0S2) directly inhibits activity of a key intracellular adipose triglyceride lipase (ATGL). PMID: 26318046
- Results indicate that G0S2 acts as a prosurvival molecule in endothelial cells. PMID: 25588877
- Data indicate that the peptide corresponding to residues Lys-20 to Ala-52 from G0S2 Inhibits ATGL in the nanomolar range. PMID: 25258314
- reelin expression is altered by Abeta leading to impaired reelin signaling. PMID: 23951308
- A new mechanism that controls proliferation in K562 cells, suggesting a possible tumor suppressor function for G0S2 in leukemia cells. PMID: 24183236
- This linked G0S2 subcellular localization to G0S2 transcriptional repression. The potential mechanisms responsible for this G0S2 repression are examined. PMID: 23546556
- Data indicate that downregulation of G0S2 in adipose tissue could represent one of the underlying causes leading to increased lipolysis in the insulin-resistant state. PMID: 22891293
- Gene expression profiles showed that G0/G1 switch 2 was up-regulated in epidermolysis bullosa subtypes. PMID: 22716248
- Reduced mRNA and protein content of Plin and G0S2 and borderline increased ATGL protein in sc adipose tissue from poorly controlled type 2 diabetic subjects. PMID: 22535977
- findings are compatible with the notion that the ATGL-G0S2 complex is an important long-term regulator of lipolysis under physiological conditions such as fasting in humans PMID: 21613358
- DNA methylation of G0S2 can be an important biomarker for squamous lung cancer. PMID: 19816938
- mRNA expression of G0S2 was regulated mainly by DNA methylation in squamous lung cancer cell lines. PMID: 19878646
- A novel putative target gene of PPARalpha, G0S2 (G0/G1 switch gene 2) was identified and characterized. PMID: 16086669
- G0S2 is an all-trans-retinoic acid target gene PMID: 18636162
- G0S2 encodes a mitochondrial protein that specifically interacts with Bcl-2 and promotes apoptosis by preventing the formation of protective Bcl-2/Bax heterodimers PMID: 19706769
顯示更多
收起更多
-
亞細胞定位：Mitochondrion.
-
組織特異性：Widely expressed with highest levels in peripheral blood, skeletal muscle and heart, followed by kidney and liver.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
