FYCO1 Antibody, FITC conjugated
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中文名稱：FYCO1兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA866262LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) FYCO1 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：CATC2 antibody; CTRCT18 antibody; DKFZp779K1152 antibody; FLJ13335 antibody; FYCO1 antibody; FYCO1_HUMAN antibody; FYVE and coiled coil domain containing 1 antibody; FYVE and coiled coil domain containing protein 1 antibody; FYVE and coiled-coil domain-containing protein 1 antibody; MGC126517 antibody; MGC126519 antibody; RUFY3 antibody; RUN and FYVE domain containing 3 antibody; ZFYVE7 antibody; Zinc finger FYVE domain containing protein 7 antibody; Zinc finger FYVE domain-containing protein 7 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human FYVE and coiled-coil domain-containing protein 1 protein (2-255AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：May mediate microtubule plus end-directed vesicle transport.
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基因功能參考文獻：
- FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation PMID: 29196475
- FYCO1 and MAP1LC3A interact through a novel binding mode that involves Atg8-family proteins PMID: 27246247
- Rare missense variants in FYCO1 are overrepresented in sporadic inclusion body myositis patients. PMID: 28009083
- FYCO1 requires a functional LC3A/B-preferring LC3-interacting Region (LIR) motif to facilitate efficient maturation of autophagosomes under basal conditions, whereas starvation-induced autophagy was unaffected PMID: 26468287
- FYCO1 is involved in lens development and transparency in humans, and mutations in this gene are one of the most common causes of autosomal-recessive congenital cataracts in the Pakistani population. PMID: 21636066
- We have characterized the LC3-, Rab7-, and phosphatidylinositol-3-phosphate-binding domains in FYCO1 and mapped part of the CC region essential for MT plus end-directed transport. PMID: 20100911
- Maps to a region of chromosome 3p21.3 which is frequently deleted in tumors. PMID: 11896456
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相關(guān)疾病：Cataract 18 (CTRCT18)
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亞細(xì)胞定位：Cytoplasmic vesicle, autophagosome. Endosome. Lysosome. Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on the external surface of autolysosomes.
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組織特異性：Expressed in heart and skeletal muscle.
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數(shù)據(jù)庫鏈接：
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