FTSJ1 Antibody

文獻引用 (1) 說明書

中文名稱：

FTSJ1兔多克隆抗體
貨號：

CSB-PA009055LA01HU
規格：

￥440
圖片：
Western blot
All lanes: FTSJ1 antibody at 2µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Mouse brain tissue
Lane 3: EC109 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 37, 36 kDa
Observed band size: 37 kDa

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA009055LA01HU at dilution of 1:50
其他：

產品詳情
產品評價
引用文獻
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FTSJ1 Polyclonal antibody
Uniprot No.：

Q9UET6
基因名：

FTSJ1
別名：

CDLIV antibody; FTSJ 1 antibody; FtsJ homolog 1 (E. coli) antibody; FtsJ homolog 1 antibody; FtsJ RNA methyltransferase homolog 1 antibody; FTSJ1 antibody; JM23 antibody; Mental retardation X linked 44 antibody; Mental retardation X linked 9 antibody; MRX44 antibody; MRX9 antibody; Protein ftsJ homolog 1 antibody; Putative ribosomal RNA methyltransferase 1 antibody; RRMJ1 antibody; RRMJ1_HUMAN antibody; rRNA (uridine 2' O ) methyltransferase antibody; rRNA (uridine-2''-O-)-methyltransferase antibody; SPB1 antibody; TRM7 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Putative tRNA (cytidine(32)/guanosine(34)-2\'-O)-methyltransferase protein (1-329AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，FTSJ1 Antibody (CSB-PA009055LA01HU)，的標記方式是Non-conjugated。對于FTSJ1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA009055LB01HU	FTSJ1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA009055LC01HU	FTSJ1 Antibody, FITC conjugated
Biotin	CSB-PA009055LD01HU	FTSJ1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

引用文獻

Investigating the Inhibition of FTSJ1 a Tryptophan tRNA-Specific 2′-O-Methyltransferase by NV TRIDs, as a Mechanism of Readthrough in Nonsense Mutated CFTR PS Carollo,biochemistry and molecular biology,2023

產品評價

靶點詳情

功能：

Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
基因功能參考文獻：
1. we have provided strong evidence that human FTSJ1 is required for Cm32 and Gm34 modification of tRNAPhe. PMID: 26310293
2. May play a role in the regulation of translation. Mutations cause X-linked mental retardation. PMID: 15162322
3. A splice site mutation is associated with non-syndromic mental retardation in a large Belgian family PMID: 15342698
4. A 50kb deletion at Xp11.23 including the two genes, SLC38A5 and FTSJ1 was found in 3 brothers with moderate to severe mental retardation. PMID: 17333282
5. identified a novel FTSJ1 mutation in an X-linked mental retardation family through mutation screening of a cohort of 73 unrelated Japanese male probands with MR PMID: 18081026
6. Results suggest a positive association between genetic variants and nonsyndromic X-linked mental retardation in young male subjects in the Chinese Han population. PMID: 18401546
7. These findings suggest that genetic variations in FtsJ homolog 1 (E. coli) possibly influence human cognitive ability. PMID: 19012053
8. Spb1p is a homologous yeast nucleolar protein PMID: 10648622
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相關疾?。?/div>
Mental retardation, X-linked 44 (MRX44)
亞細胞定位：

Cytoplasm.
蛋白家族：

Class I-like SAM-binding methyltransferase superfamily, RNA methyltransferase RlmE family, TRM7 subfamily
組織特異性：

Found in fetal brain, lung, liver and kidney. In the adult brain, expressed in amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus.
數據庫鏈接：

HGNC: 13254

OMIM: 300499

KEGG: hsa:24140

STRING: 9606.ENSP00000326948

UniGene: Hs.23170

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