FSD1 Antibody

中文名稱：

FSD1兔多克隆抗體
貨號：

CSB-PA861136LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA861136LA01HU diluted at 1:500 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA861136LA01HU diluted at 1:500 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FSD1 Polyclonal antibody
Uniprot No.：

Q9BTV5
基因名：

FSD1
別名：

Fibronectin type 3 and SPRY (spla; ryanodine) domain containing (with coiled-coil motif) 1 antibody; Fibronectin type 3 and SPRY domain containing 1 antibody; Fibronectin type III and SPRY domain containing 1 antibody; Fibronectin type III and SPRY domain-containing protein 1 antibody; Fibronectin type III and SPRY domains containing protein 1 antibody; FSD1 antibody; FSD1_HUMAN antibody; GLFND antibody; MGC3213 antibody; MGC58341 antibody; Microtubule-associated protein GLFND antibody; MID1-related protein 1 antibody; midline 1-related protein 1 antibody; MIR1 antibody; VLP27 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Fibronectin type III and SPRY domain-containing protein 1 protein (251-370AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，FSD1 Antibody (CSB-PA861136LA01HU)，的標記方式是Non-conjugated。對于FSD1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA861136LB01HU	FSD1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA861136LC01HU	FSD1 Antibody, FITC conjugated
Biotin	CSB-PA861136LD01HU	FSD1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:500-1:1000

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

May be involved in microtubule organization and stabilization.
基因功能參考文獻：
1. Overexpression of miR-1 mimics significantly decreased tumor glycolysis, including lactate production and glucose uptake, and cell proliferation, and these effects were reversed by ectopic expression of Smad3. PMID: 28471448
2. These regulatory mechanisms of miR-1 expression could help us to understand the functions of altered miR-1 expression. PMID: 27923712
3. Taken together, our findings established a tumor suppressive role for miR-1 in the progression of ccRCC by targeting CDK4, CDK6, Caprin1 and Slug and suggested miR-1 can be served as a novel potential therapeutic target for ccRCC. PMID: 26036633
4. Data report the identification of MIR1, a protein with microtubule-binding activity which is located at the centrosome and is related to MID1/midin. [MIR1] PMID: 12154070
亞細胞定位：

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
組織特異性：

Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
數據庫鏈接：

HGNC: 13745

OMIM: 609828

KEGG: hsa:79187

STRING: 9606.ENSP00000221856

UniGene: Hs.28144

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