FMO2 Antibody

說明書

中文名稱：

FMO2兔多克隆抗體
貨號：

CSB-PA857449ESR1HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA857449ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA857449ESR1HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FMO2 Polyclonal antibody
Uniprot No.：

Q99518
基因名：

FMO2
別名：

2310008D08Rik antibody; 2310042I22Rik antibody; AW107733 antibody; Dimethylaniline monooxygenase [N oxide forming] 2 antibody; Dimethylaniline monooxygenase [N-oxide-forming] 2 antibody; Dimethylaniline oxidase 2 antibody; Flavin containing monooxygenase 2 (non functional) antibody; Flavin containing monooxygenase 2 antibody; FLJ40826 antibody; FMO 1B1 antibody; FMO 2 antibody; FMO antibody; FMO pulmonary antibody; FMO1B1 antibody; FMO2 antibody; FMO2_HUMAN antibody; MGC28212 antibody; OTTMUSP00000028686 antibody; OTTMUSP00000028687 antibody; Pulmonary flavin containing monooxygenase 2 antibody; Pulmonary flavin-containing monooxygenase 2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Dimethylaniline monooxygenase [N-oxide-forming] 2 protein (210-470AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole.
基因功能參考文獻：
1. study provides an evidence for the existence of an evolutionary adaptation to an ancient disease based on an ancestral genetic variant acting in a FMO2 haplotypic framework in Ethiopian populations PMID: 28981537
2. analysis of flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics PMID: 15864117
3. analysis of how the functional variant flavin-containing monooxygenase 2*1 is at high frequency throughout sub-Saharan Africa PMID: 18794725
4. Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K. PMID: 19420133
亞細胞定位：

Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
蛋白家族：

FMO family
組織特異性：

Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain.
數據庫鏈接：

HGNC: 3770

OMIM: 603955

KEGG: hsa:2327

STRING: 9606.ENSP00000209929

UniGene: Hs.144912

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