FKBPL Antibody
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中文名稱：FKBPL兔多克隆抗體
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貨號：CSB-PA050004
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：FKBPL
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別名：DIR1 antibody; FK506 binding protein like antibody; FK506-binding protein-like antibody; Fkbpl antibody; FKBPL_HUMAN antibody; NG7 antibody; OTTHUMP00000029170 antibody; WAF 1/CIP1 stabilizing protein 39 antibody; WAF-1/CIP1 stabilizing protein 39 antibody; WISP39 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the C-terminal region of Human FKBPL.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
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基因功能參考文獻：
- This study identified two low-frequency nonsynonymous variants at FKBPL (rs200847762, OR = 0.34, 95% CI = 0.20-0.57, P = 4.31 x 10-5) and ARPC1B (rs1045012, OR = 0.56, 95% CI = 0.43-0.74, P = 4.30 x 10-5) associated with breast cancer risk. PMID: 27479355
- The data suggests a role for FKBPL as a prognostic factor for BCSS, with the potential to be routinely evaluated within the clinic. PMID: 25906750
- WISp39 preferentially interacts with phosphorylated Coronin 1B, allowing it to complex with Slingshot phosphatase to dephosphorylate and activate Cofilin. PMID: 25800056
- FKBPL is an important regulator of developmental and pathological angiogenesis. PMID: 25767277
- high levels of FKBPL and RBCK1 correlated with increased patient survival, whereas high RBCK1 predicted for a poor response to tamoxifen. PMID: 23912458
- FKBPL and and its peptide derivative, AD-01 regulate expression of CD44. PMID: 23457460
- Genome-wide association study of age-related macular degeneration identifies TNXB, FKBPL and NOTCH4 as candidate susceptibility genes. PMID: 22694956
- Alterations in the gene for FKBPL in azoospermic patients. PMID: 20210997
- Findings suggest that FKBPL may have prognostic value based on its impact on tumor proliferative capacity and sensitivity to endocrine therapies, which improve outcome. PMID: 20103631
- Results demonstrate the importance of posttranslational stabilization of p21 protein by WISp39 in regulating cellular p21 activity. PMID: 15664193
- FKBPL can be classed as a new member of the FKBP protein family with a role in steroid receptor complexes and signaling. PMID: 18669603
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組織特異性：Ubiquitously expressed with higher levels in testis.
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數據庫鏈接：
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