FKBP3 Antibody

中文名稱：

FKBP3兔多克隆抗體
貨號：

CSB-PA008699HA01HU
規(guī)格：

￥440
圖片：
Western blot
All lanes: FKBP3 antibody at 4µg/ml
Lane 1: Hela whole cell lysate
Lane 2: A431 whole cell lysate
Lane 3: PC-3 whole cell lysate
Lane 4: Jurkat whole cell lysate
Lane 5: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 26 kDa
Observed band size: 26 kDa

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA008699HA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA008699HA01HU at dilution of 1:100

Immunofluorescent analysis of A549 cells using CSB-PA008699HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產(chǎn)品詳情
產(chǎn)品評價
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靶點詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) FKBP3 Polyclonal antibody
Uniprot No.：

Q00688
基因名：

FKBP3
別名：

25 kDa FK506-binding protein antibody; 25 kDa FKBP antibody; FK506 binding protein 25 T cell antibody; FK506 binding protein 25; T cell; 25-KD antibody; FK506 binding protein 3 (25kD) antibody; FK506-binding protein 3 antibody; FKBP 25 antibody; FKBP 3 antibody; FKBP-25 antibody; FKBP-3 antibody; FKBP25 antibody; FKBP3 antibody; FKBP3_HUMAN antibody; Immunophilin FKBP25 antibody; Peptidyl-prolyl cis-trans isomerase FKBP3 antibody; PPIase antibody; PPIase FKBP3 antibody; Rapamycin binding protein antibody; Rapamycin-selective 25 kDa immunophilin antibody; Rotamase antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP3 protein (2-224AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，F(xiàn)KBP3 Antibody (CSB-PA008699HA01HU)，的標(biāo)記方式是Non-conjugated。對于FKBP3 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA008699HB01HU	FKBP3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA008699HC01HU	FKBP3 Antibody, FITC conjugated
Biotin	CSB-PA008699HD01HU	FKBP3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

功能：

FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
基因功能參考文獻：
1. Taken together, these data clearly show that FKBP3/Sp1/HDAC2/p27 control cell proliferation during non-small cell lung cancer development. PMID: 28839465
2. Data show that the N-terminus of FK506 binding protein-25 (FKBP25) is anchored to regions of dsRNA, whereas the FKBP domain is free to interact with neighboring proteins. PMID: 29036638
3. Structural basis for nucleic acid recognition by FKBP25 has been uncovered. PMID: 26762975
4. proteomics study indicates that the nuclear pool of the FKBP25 targets various nuclear proteins that are crucial for packaging of DNA, chromatin remodeling and pre-mRNA splicing PMID: 24998444
5. FKBP25 is likely recruited to preribosomes to chaperone one of the protein components of the ribosome large subunit. PMID: 24840943
6. structure of a unique N-terminal domain motif in the FKBP family, FKBP25(1-73), high-resolution structures show a new fold composed of five small helices where H3 and H4 are tilted in a novel arrangement; called Basic Tilted Helix Bundle (BTHB) domain. PMID: 24667607
7. FKBP3, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53. PMID: 19166840
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亞細胞定位：

Nucleus.
蛋白家族：

FKBP-type PPIase family
數(shù)據(jù)庫鏈接：

HGNC: 3719

OMIM: 186947

KEGG: hsa:2287

STRING: 9606.ENSP00000216330

UniGene: Hs.509226

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