FGL1 Antibody
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中文名稱：FGL1兔多克隆抗體
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貨號：CSB-PA004850
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規格：￥1090
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圖片：
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Western Blot analysis of mouse liver cells using Hepassocin Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：FGL1
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別名：FGL 1 antibody; Fgl1 antibody; FGL1_HUMAN antibody; Fibrinogen like 1 antibody; Fibrinogen like protein 1 antibody; Fibrinogen related protein 1 antibody; Fibrinogen-like protein 1 antibody; Hepassocin antibody; Hepatocellular carcinoma related sequence antibody; Hepatocyte derived fibrinogen related protein 1 antibody; Hepatocyte-derived fibrinogen-related protein 1 antibody; HFREP 1 antibody; HFREP-1 antibody; HFREP1 antibody; HP 041 antibody; HP-041 antibody; HP041 antibody; LFIRE 1 antibody; LFIRE-1 antibody; LFIRE1 antibody; Liver fibrinogen related protein 1 antibody; Liver fibrinogen-related protein 1 antibody; MFIRE 1 antibody; MGC108569 antibody; MGC12455 antibody; MGC37822 antibody; OTTHUMP00000122468 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the Internal region of Human Hepassocin.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes.
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基因功能參考文獻：
- FGL1 promotes invasion and metastasis of gastric cancer and is associated with poor prognosis. PMID: 29845203
- findings highlight the crucial role of HFREP1 in insulin resistance and diabetes, and provide a potential strategy and biomarker for developing therapeutic approaches to combat these diseases. PMID: 27221093
- Hepassocin plays an important role in non-alcoholic fatty liver disease and induces hepatic lipid accumulation through an ERK1/2-dependent pathway. PMID: 23792031
- Here, the application of small ubiquitin-related modifier (SUMO) fusion technology in combination with four different chaperone teams on the soluble expression of recombinant HPS protein was explored and analyzed. PMID: 24084006
- Findings suggest that hepassocin promotes hepatic cell line L02 cells proliferation via an autocrine mechanism and inhibits HCC cells proliferation by an intracrine pathway. PMID: 21618590
- data demonstrated that liver-specific gene LFIRE-1/HFREP-1 was frequently downregulated and might possess growth suppressor activity in HCC PMID: 14981537
- HFREP-1 in plasma almost completely bound to the fibrin matrix during clot formation PMID: 16996032
- The enhancement of FGL1 levels in vitro by IL-6 and its induction after turpentine oil injection suggest that it is an acute phase reactant. PMID: 18039467
- HNF1 binding site and HNF1alpha are critical to liver-specific expression of HPS, and down-regulation or loss of HNF1alpha causes, at least in part, the transcriptional down-regulation of HPS in HCC. PMID: 19304666
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亞細胞定位：Secreted.
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組織特異性：Under normal conditions, liver-specific.
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數據庫鏈接：
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