FGF20 Antibody
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中文名稱：FGF20兔多克隆抗體
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貨號：CSB-PA059543
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA059543(FGF20 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA059543(FGF20 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：FGF-20 antibody; Fgf20 antibody; FGF20_HUMAN antibody; FGFK antibody; Fibroblast growth factor 20 antibody; RHDA2 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic peptide of Human FGF20
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Neurotrophic factor that regulates central nervous development and function.
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基因功能參考文獻：
- Studied effect of recombinant human fibroblast growth factor 20 (rhFGF20) on cultured mouse vibrissal follicles; found rhFGF20 significantly induced growth of the follicles in vitro, stimulated proliferation of hair matrix cells, and activated Wnt signal pathway. PMID: 29713847
- This study confirmed that the A allele of rs591323 in FGF20 reduces the risk of developing sporadic PD (P = 0.013). Additionally, subjects with the AA + AG genotype have a reduced risk compared to individuals with the GG genotype (P = 0.024). PMID: 28238162
- the FGF20 gene might not play a dominating role in the genetic predisposition to essential tremor in Chinese Han population. PMID: 27040428
- Meta-analysis indicated that the rs12720208 polymorphism may be associated with the Parkinson's disease susceptibility in Caucasians PMID: 28191856
- This study suggested that there is no sufficient evidence to support the association between FGF20 rs12720208 polymorphism and Parkinson's disease risk. PMID: 27023076
- The results of this study indicated that rs12720208 may contribute to the risk of PD in Iranian population. PMID: 26070653
- Meta-analysis suggests that FGF20 rs1721100 C/G polymorphism is associated with sporadic sporadic Parkinson's diseases in Asians PMID: 25030126
- The meta-analysis showed an association between FGF20 gene rs1721100 polymorphism and risk of Parkinson's disease under a recessive model. PMID: 24942208
- The results showed no significant differences in the presence of rs1721100 or rs12720208 in the FGF20 gene between Parkinson's disease patients and controls. PMID: 23938014
- The results have not shown any effect of rs12720208 in the FGF20 gene on the risk of Parkinson's disease in patients residing in Russia PMID: 23516905
- This study revealed that the rs1721100(C/G) polymorphism is a risk factor for PD in Han Chinese population, while rs12720208(C/T) polymorphism is not significantly associated with Parkinson's disease. PMID: 22342445
- The data suggested that Fgf9/20 and Bmp7 organize the nephron progenitor niche and highlight the essential role of FGF20 in human kidney development. FGF signaling likely regulates multiple important steps in the stem cell niche. PMID: 22698282
- The common FGF20 rs12720208 SNP was not associated with the risk for Parkinson's disease (PD) in our population. In addition, we did not find nucleotide changes in miR-433 (that binds to the 3' UTR FGF20 mRNA) among our PD patients. PMID: 20471450
- The associations described, from mRNA expression to brain morphology to cognition and an interaction with aging, confirm a role of FGF20 in human brain structure and function during development and aging. PMID: 20427658
- Fibroblast growth factor 20 polymorphisms and haplotypes is associated with the risk of Parkinson disease PMID: 15122513
- Data show that FGF20 and DKK1 appear to be direct targets for beta-catenin/TCF transcriptional regulation via LEF/TCF-binding sites, and are expressed early in Xenopus embryogenesis under the control of the Wnt signaling pathway PMID: 15592430
- results suggest that the FGF20 gene is a susceptibility gene for Parkinson's disease in the Japanese population PMID: 17515805
- Variants in FGF20 and MAOB show evidence of statistical interactions and potential patterns of biological interaction contributing to Parkinson disease risk. PMID: 18205889
- Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. PMID: 18252210
- FGF20 is associated with Parkinson's disease synergistically with SNCA. PMID: 18568448
- Data demonstrate that homodimerization autoregulates FGF9 and FGF20's receptor binding and concentration gradients in the extracellular matrix. PMID: 19564416
- The effect of arginine on the solubility and stability of FGF-20 was dominated by the preferential binding interaction. PMID: 19619121
- FGF20, FGF9, and FGF16 constitute a subfamily among FGFs. FGF20 is preferentially expressed in colorectal cancer. PMID: 10913340
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相關疾病：Renal hypodysplasia/aplasia 2 (RHDA2)
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亞細胞定位：Secreted.
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蛋白家族：Heparin-binding growth factors family
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組織特異性：Predominantly expressed in the cerebellum.
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數據庫鏈接：
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