FGF16 Antibody

中文名稱：

FGF16兔多克隆抗體
貨號：

CSB-PA008621LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA008621LA01HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FGF16 Polyclonal antibody
Uniprot No.：

O43320
基因名：

FGF16
別名：

FGF 16 antibody; FGF-16 antibody; Fgf16 antibody; FGF16_HUMAN antibody; Fibroblast growth factor 16 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Fibroblast growth factor 16 protein (1-207AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，FGF16 Antibody (CSB-PA008621LA01HU)，的標記方式是Non-conjugated。對于FGF16 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA008621LB01HU	FGF16 Antibody, HRP conjugated	ELISA
FITC	CSB-PA008621LC01HU	FGF16 Antibody, FITC conjugated
Biotin	CSB-PA008621LD01HU	FGF16 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.
基因功能參考文獻：
1. Experiments demonstrated FGF16 could promote proliferation of NCL-H460 cells by activating Akt, Erk1/2, and p38 MAPK signaling, whereas JNK had no significant effect. PMID: 28409700
2. Identification of an FGF16 mutation in metacarpal 4-5 fusion. PMID: 24878828
3. impaired FGF16 function may also be responsible for connective tissue symptoms in MF4 patients. PMID: 24706454
4. Fgf-16 gene is a target for NF-kappaB activation in the postnatal heart. PMID: 20097674
5. HUVEC clearly demonstrated chemotaxis towards FGF16. FGF16 enhanced cell migration in response to mechanical damage & failed to induce endothelial cell proliferation or sprouting in a three-dimensional in vitro angiogenesis assay. PMID: 16756958
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相關疾病：

Metacarpal 4-5 fusion (MF4)
亞細胞定位：

Secreted.
蛋白家族：

Heparin-binding growth factors family
數據庫鏈接：

HGNC: 3672

OMIM: 300827

KEGG: hsa:8823

STRING: 9606.ENSP00000399324

UniGene: Hs.666364

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