FEN1 Antibody

Name: FEN1 Antibody
Brand: CUSABIO
SKU: CSB-PA008585LA01DOA

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說(shuō)明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FEN1 Polyclonal antibody
Uniprot No.：

O65251
基因名：

FEN1
別名：

FEN1 antibody; At5g26680 antibody; F21E10.3Flap endonuclease 1 antibody; FEN-1 antibody; EC 3.1.-.- antibody; Flap structure-specific endonuclease 1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Arabidopsis thaliana
免疫原：

Recombinant Arabidopsis thaliana Flap endonuclease 1 protein (85-383AA)
免疫原種屬：

Arabidopsis thaliana (Mouse-ear cress)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，F(xiàn)EN1 Antibody (CSB-PA008585LA01DOA)，的標(biāo)記方式是Non-conjugated。對(duì)于FEN1 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA008585LB01DOA	FEN1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA008585LC01DOA	FEN1 Antibody, FITC conjugated
Biotin	CSB-PA008585LD01DOA	FEN1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
基因功能參考文獻(xiàn)：
1. At5g26680 role in mediating transcriptional gene silencing as well as maintaining genome stability PMID: 27231839
2. Data show that shade avoidance 6 (SAV6; At5g26680), encodes flap endonuclease-1 (FEN1), assures proper root development through maintenance of genome integrity. PMID: 26721386
亞細(xì)胞定位：

Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion.
蛋白家族：

XPG/RAD2 endonuclease family, FEN1 subfamily
數(shù)據(jù)庫(kù)鏈接：

KEGG: ath:AT5G26680

STRING: 3702.AT5G26680.1

UniGene: At.47103

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