FBXO9 Antibody

中文名稱：

FBXO9兔多克隆抗體
貨號：

CSB-PA891719LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA891719LA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA891719LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FBXO9 Polyclonal antibody
Uniprot No.：

Q9UK97
基因名：

FBXO9
別名：

Cross-immune reaction antigen 1 antibody; dJ341E18.2 antibody; DKFZp434C0118 antibody; F-box only protein 9 antibody; Fbp24 antibody; FBX09 antibody; FBX9 antibody; FBX9_HUMAN antibody; Fbxo9 antibody; KIAA0936 antibody; NY REN 57 antibody; OTTHUMP00000016628 antibody; OTTHUMP00000016629 antibody; OTTHUMP00000214588 antibody; Renal carcinoma antigen NY-REN-57 antibody; VCIA1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human F-box only protein 9 protein (13-111AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，FBXO9 Antibody (CSB-PA891719LA01HU)，的標記方式是Non-conjugated。對于FBXO9 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA891719LB01HU	FBXO9 Antibody, HRP conjugated	ELISA
FITC	CSB-PA891719LC01HU	FBXO9 Antibody, FITC conjugated
Biotin	CSB-PA891719LD01HU	FBXO9 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.
亞細胞定位：

Cytoplasm.
數據庫鏈接：

HGNC: 13588

OMIM: 609091

KEGG: hsa:26268

STRING: 9606.ENSP00000244426

UniGene: Hs.216653

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