FBXO8 Antibody
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中文名稱：FBXO8兔多克隆抗體
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貨號：CSB-PA008517GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：FBXO8
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別名：DC10 antibody; F box only protein 8 antibody; F box protein 8 antibody; F box protein Fbx8 antibody; F box/SEC7 protein FBS antibody; F-box only protein 8 antibody; F-box/SEC7 protein FBS antibody; FBS antibody; FBX8 antibody; FBX8_HUMAN antibody; FBXO 8 antibody; Fbxo8 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human FBXO8
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential).
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基因功能參考文獻：
- Study demonstrates that down-regulation of FBX8 in hepatocellular carcinoma (HCC) correlates with poor survival of patients. All of the functional experiments confirm FBX8 as a tumor suppressor in the progression of HCC. The preferential down-regulation of FBX8 in HCC patients with invasion and metastasis suggested that FBX8 may be a significant biomarker for HCC progression. PMID: 23826080
- FBX8 as a metastasis suppressor that functions through mTOR signaling pathway and has significant prognostic power. PMID: 27916606
- FBX8 down-expression was an independent prognostic indicator for glioma patient's survival. PMID: 25550853
- FBX8 was markedly down-regulated in gastric cancer tissues. Knocking down FBX8 promoted proliferation and invasion in tumor cell line. Patients with low FBX8 had poor prognosis. PMID: 25801334
- FBX8 is a novel c-Myc binding protein and that c-Myc induces cell invasive activity PMID: 20848231
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