FAR1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FAR1 Polyclonal antibody
Uniprot No.：

Q8WVX9
基因名：

FAR1
別名：

FAR1; MLSTD2; UNQ2423/PRO4981; Fatty acyl-CoA reductase 1; Male sterility domain-containing protein 2
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Fatty acyl-CoA reductase 1 protein (182-343AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols. In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis.
基因功能參考文獻：
1. A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency. PMID: 25439727
2. Expression of Far1 increased plasmalogen synthesis in wild-type Chinese hamster ovary cells, strongly suggesting that Far1 is a rate-limiting enzyme for plasmalogen synthesis. PMID: 24108123
3. ether lipid biosynthesis in mammalian cells is regulated by a negative feedback mechanism that senses cellular plasmalogen levels and appropriately increases or decreases Far1 PMID: 20071337
相關疾病：

Peroxisomal fatty acyl-CoA reductase 1 disorder (PFCRD)
亞細胞定位：

Peroxisome membrane; Single-pass membrane protein.
蛋白家族：

Fatty acyl-CoA reductase family
數據庫鏈接：

HGNC: 26222

OMIM: 616107

KEGG: hsa:84188

STRING: 9606.ENSP00000346874

UniGene: Hs.501991

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