FANK1 Antibody

中文名稱：

FANK1兔多克隆抗體
貨號：

CSB-PA819458HA01HU
規格：

￥440
圖片：
Immunofluorescence staining of MCF-7 cells with CSB-PA819458HA01HU at 1:333, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA819458HA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FANK1 Polyclonal antibody
Uniprot No.：

Q8TC84
基因名：

FANK1
別名：

1700007B22Rik antibody; AI850911 antibody; Fank1 antibody; FANK1_HUMAN antibody; Fibronectin type 3 and ankyrin repeat domains 1 antibody; Fibronectin type 3 and ankyrin repeat domains protein 1 antibody; Fibronectin type III and ankyrin repeat domains 1 antibody; HSD13 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Fibronectin type 3 and ankyrin repeat domains protein 1 protein (1-345AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，FANK1 Antibody (CSB-PA819458HA01HU)，的標記方式是Non-conjugated。對于FANK1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA819458HB01HU	FANK1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA819458HC01HU	FANK1 Antibody, FITC conjugated
Biotin	CSB-PA819458HD01HU	FANK1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis.
基因功能參考文獻：
1. RYBP activates FANK1-mediated activator protein 1 (AP-1) signaling pathway which contributes to tumor cell apoptosis. PMID: 27060496
2. we find evidence for many novel candidates, the strongest of which is FANK1, an imprinted gene that suppresses apoptosis, is expressed during meiosis in males. PMID: 25144706
3. the TNfnIII 1-5 repeats play an important role in PCO pathology. PMID: 25515583
4. found that Jab1 (Jun activation domain-binding protein 1), a co-activator of AP-1, specifically interacted with Fank1 PMID: 20978819
5. FANK1 may have a role in regulating gene expression in the transition from the meiotic phase to the haploid phase during spermatogenesis PMID: 17604233
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亞細胞定位：

Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium.
組織特異性：

Mostly restricted to testis.
數據庫鏈接：

HGNC: 23527

OMIM: 611640

KEGG: hsa:92565

STRING: 9606.ENSP00000357682

UniGene: Hs.352591

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