FAM83D Antibody, Biotin conjugated
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中文名稱：FAM83D兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA887979LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) FAM83D Polyclonal antibody
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Uniprot No.：
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基因名：FAM83D
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別名：2310007D09Rik antibody; BB104611 antibody; C20orf129 antibody; CHICA antibody; dJ616B8.3 antibody; FA83D antibody; FA83D_HUMAN antibody; FAM83D antibody; Family with sequence similarity 83; member D antibody; FLJ38341 antibody; MGC92947 antibody; Protein FAM83D antibody; RGD1565583 antibody; RP23-119H5.1 antibody; Spindle protein CHICA antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Protein FAM83D protein (339-470AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC. May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade. May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.
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基因功能參考文獻：
- FAM83D promotes HCC recurrence by promoting CD44 expression and CD44+ CSCs malignancy. PMID: 27769048
- Higher level of FAM83D expression is positively correlated with an increase in genome instability in many cancer. PMID: 26678035
- upregulation of FAM83D, a potential oncotarget gene, may be triggered by epigenetic events and can contribute to hepatocarcinogenesis PMID: 26125229
- NMR-derived secondary chemical shifts and relaxation properties show that the Chica LC8 binding domain is essentially disordered with a dynamically restricted segment in one linker between motifs. PMID: 26652654
- Taken together, these results demonstrate that FAM83D is a novel oncogene in HCC development and may constitute a potential therapeutic target in HCC. PMID: 25646692
- Results demonstrate that FAM83D has prognostic value for breast cancer patients and is a novel oncogene in breast cancer development that at least in part acts through mTOR hyper-activation by inhibiting FBXW7. PMID: 24344117
- interaction partner of the chromokinesin Kid that is required for the generation of polar ejection forces and chromosome congression PMID: 18485706
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亞細胞定位：Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
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蛋白家族：FAM83 family
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組織特異性：Expressed in the testis.
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數據庫鏈接：
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