FAM49B Antibody
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中文名稱：FAM49B兔多克隆抗體
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貨號：CSB-PA008253GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：FAM49B
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別名：BM 009 antibody; FA49B_HUMAN antibody; Fam49b antibody; Family with sequence similarity 49; member B antibody; L1 antibody; Protein FAM49B antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human FAM49B
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC,IF
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling. Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization. Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry. Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes. Involved in the regulation of mitochondrial dynamics and oxidative stress.
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基因功能參考文獻：
- FAM49B inhibits T cell activation by repressing Rac activity and modulating cytoskeleton reorganization. PMID: 29632189
- Three proteins-matrix metalloproteinase-9, neutrophil elastase, and FAM49B-were significantly lower in abundance in samples from women with endometriosis. PMID: 25284053
- FAM49B is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
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亞細胞定位：Membrane; Lipid-anchor. Mitochondrion.
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蛋白家族：FAM49 family
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數據庫鏈接：
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