FAM129B (Ab-712) Antibody
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中文名稱：FAM129B (Ab-712)兔多克隆抗體
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貨號：CSB-PA998601
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規(guī)格：￥2024
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圖片：
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Western blot analysis of extracts from 3T3 and DU145 cells using Niban-like protein(Ab-712) antibody. -
Immunofluorescence staining of methanol-fixed Hela cells using Niban-like protein(Ab-712) antibody.
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) FAM129B Polyclonal antibody
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Uniprot No.：
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基因名：FAM129B
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Peptide sequence around aa.710~714 (Q-V-S-S-P) derived from Human Niban-like protein.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Liquid
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應用范圍：ELISA,WB,IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:1000 IF 1:100-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro.
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基因功能參考文獻：
- activated EGFR phosphorylates the Y593 residue of the protein known as family with sequence similarity 129, member B (FAM129B), which is overexpressed in many types of human cancer. PMID: 26721396
- The rapid induction of apoptosis in FAM129B knockdown cells was reversed by co-transfection with recombinant FAM129B, indicating that its effect on apoptosis was specific. PMID: 21148485
- Phosphorylation of FAM129B has a role in controlling melanoma cell invasion. PMID: 19362540
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亞細胞定位：Cytoplasm, cytosol. Cell junction, adherens junction. Membrane; Lipid-anchor. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation.
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蛋白家族：Niban family
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數(shù)據(jù)庫鏈接：
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