Ets21C Antibody

^{Rare Species}

說明書

產品詳情

Uniprot No.：

P29776
基因名：

Ets21C
別名：

DNA-binding protein D-ETS-6 Ets21C ETS-6 CG2914
反應種屬：

Drosophila melanogaster (Fruit fly)
免疫原：

Recombinant Drosophila melanogaster (Fruit fly) Ets21C protein (165-334aa)
免疫原種屬：

Drosophila melanogaster (Fruit fly)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Affinity-chromatography
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻：
1. Data show that Ets21C has a crucial role in the regulation of tumor growth as a loss of function critically reduced tumor growth, whereas an excess of Ets21C further increased tumor size. While Ets21C was shown only with a role in fine-tuning the transcriptional program of neoplastic tumors, results point towards a more fundamental role as activator of a specific set of target genes driving tumor growth and invasion. PMID: 27713480
2. malignant transformation of the ras(V12)scrib(1) tumors requires bZIP protein Fos, the ETS-domain factor Ets21c and the nuclear receptor Ftz-F1, all acting downstream of Jun-N-terminal kinase. PMID: 26398940
3. These studies identify Cic, Pnt, and Ets21C as critical downstream effectors of EGFR signaling in Drosophila Intestinal Stem Cells PMID: 26683696
亞細胞定位：

Nucleus.
蛋白家族：

ETS family
組織特異性：

Embryonic ventral nervous system and 1 pair of neurons in each thoracic segment.
數據庫鏈接：

KEGG: dme:Dmel_CG2914

STRING: 7227.FBpp0077739

UniGene: Dm.21518

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