Efna1 Antibody

Name: Efna1 Antibody
Brand: CUSABIO
SKU: CSB-PA007460LA01RA

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說明書

產品詳情

產品名稱：

Rabbit anti-Rattus norvegicus (Rat) Efna1 Polyclonal antibody
Uniprot No.：

P97553
基因名：

Efna1
別名：

Efna1 antibody; Epgl1 antibody; Lerk1 antibody; Ephrin-A1 antibody; EPH-related receptor tyrosine kinase ligand 1 antibody; LERK-1 antibody; Immediate early response protein B61) [Cleaved into: Ephrin-A1 antibody; secreted form] antibody
宿主：

Rabbit
反應種屬：

Rat
免疫原：

Recombinant Rat Ephrin-A1 protein (18-182AA)
免疫原種屬：

Rattus norvegicus (Rat)

標記方式：

Non-conjugated

本頁面中的產品，Efna1 Antibody (CSB-PA007460LA01RA)，的標記方式是Non-conjugated。對于Efna1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA007460LB01RA	Efna1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA007460LC01RA	Efna1 Antibody, FITC conjugated
Biotin	CSB-PA007460LD01RA	Efna1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.
亞細胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.; [Ephrin-A1, secreted form]: Secreted.
蛋白家族：

Ephrin family
數據庫鏈接：

KEGG: rno:94268

STRING: 10116.ENSRNOP00000027920

UniGene: Rn.8427

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