EVL Antibody
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中文名稱：EVL兔多克隆抗體
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貨號：CSB-PA007869GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：EVL
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別名：EVL antibody; RNB6Ena/VASP-like protein antibody; Ena/vasodilator-stimulated phosphoprotein-like antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human EVL
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization.
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基因功能參考文獻：
- EVL/miR-342 methylation was preferentially detected in IgD multiple myeloma PMID: 29242101
- Identify CRMP-1 as a novel regulator of actin filament elongation and reveal a surprisingly important role for CRMP-1, EVL, and actin polymerization in maintaining the structural integrity of epithelial sheets. PMID: 28630144
- ENA/VASP-family proteins are functionally redundant in homologous recombination, and MENA, VASP and EVL may be involved in the DSB repair pathway in humans PMID: 21398369
- EVL, with either E. coli topoisomerase I or human topoisomerase IIIalpha, catalyzed ssDNA catenation. PMID: 20639531
- Ena/VASP proteins regulate actin polymerization at actin filament barbed ends in vitro in the presence and absence of barbed end capping proteins. PMID: 15939738
- the interaction of the alphaII-spectrin SH3 domain with EVL PMID: 16336193
- Data suggest that ena/VASP binding to F-actin allows for gephyrin recruitment to the leading edge of uncapped actin filaments. PMID: 16376568
- EVL is required for endothelial barrier function in vivo. PMID: 17998398
- A microRNA encoded in an intron of the gene EVL, is commonly suppressed in human colorectal cancer. PMID: 18264139
- EVL may be implicated in invasion and/or metastasis of human breast cancer. PMID: 18357390
- EVL protein is a novel recombination factor that may be required for repairing specific DNA lesions, and that may cause tumor malignancy by its inappropriate expression. PMID: 19329439
- EVH2 domain, which is highly conserved among the ENA/VASP family proteins, may be responsible for the recombination function of EVL. PMID: 19725871
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亞細胞定位：Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cell projection, lamellipodium.
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蛋白家族：Ena/VASP family
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數據庫鏈接：
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