ERP27 Antibody, FITC conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ERP27 Polyclonal antibody
Uniprot No.：

Q96DN0
基因名：

ERP27
別名：

C12orf46 antibody; Chromosome 12 open reading frame 46 antibody; Endoplasmic reticulum protein 27 antibody; Endoplasmic reticulum protein 27 kDa antibody; Endoplasmic reticulum resident protein 27 antibody; Endoplasmic reticulum resident protein ERp27 antibody; ER protein 27 antibody; ERp 27 antibody; ERp27 antibody; ERP27_HUMAN antibody; FLJ32115 antibody; PDIA8 antibody; Protein disulfide isomerase family A; member 8 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Endoplasmic reticulum resident protein 27 protein (26-273AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates. Binds protein substrates via a hydrophobic pocket in the C-terminal domain. May play a role in the unfolded stress response.
基因功能參考文獻：
1. High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility PMID: 23234573
2. ERp27 is able to distinguish between folded and unfolded substrates, only interacting with the latter and presenting them to for catalysis. PMID: 23192347
3. ERp27 is bound by ERp57 both in vitro and in vivo by a similar mechanism by which ERp57 binds calreticulin PMID: 16940051
亞細胞定位：

Endoplasmic reticulum lumen.
蛋白家族：

Protein disulfide isomerase family
數據庫鏈接：

HGNC: 26495

OMIM: 610642

KEGG: hsa:121506

STRING: 9606.ENSP00000266397

UniGene: Hs.162143

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