ERGIC3 Antibody

說明書

產品詳情

Uniprot No.：

Q9Y282
基因名：

ERGIC3
別名：

2310015B14Rik antibody; AV318804 antibody; C20orf47 antibody; CGI 54 antibody; D2Ucla1 antibody; dJ477O4.2 antibody; DKFZp547A2190 antibody; Endoplasmic reticulum Golgi intermediate compartment protein 3 antibody; endoplasmic reticulum localized protein ERp43 antibody; Endoplasmic reticulum-Golgi intermediate compartment protein 3 antibody; ERGI3_HUMAN antibody; ERGIC and golgi 3 antibody; ergic3 antibody; ERV46 antibody; NY BR 84 antibody; PRO0989 antibody; RP23-220D12.2 antibody; RP3-477O4.1 antibody; SDBCAG84 antibody; Serologically defined breast cancer antigen 84 antibody; Serologically defined breast cancer antigen NY BR 84 antibody; Serologically defined breast cancer antigen NY-BR-84 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the C-terminal region of Human ERGIC-3.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, IHC, IF, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Possible role in transport between endoplasmic reticulum and Golgi.
基因功能參考文獻：
1. these data showed that knockdown of ERGIC3 triggers endoplasmic reticulum stress-induced autophagic cancer cell death PMID: 27588471
2. Results showed that miR-203a downregulation induced ERGIC3 overexpression in non-small cell lung cancer cells. PMID: 26177443
3. ERGIC3 may play an active role in the development and progression of lung cancer. PMID: 23374247
4. miR-490-3p modulates cell growth and epithelial to mesenchymal transition of hepatocellular carcinoma cells by targeting endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3). PMID: 23212913
5. Plays important roles in cell growth and endoplasmic reticulum stress-induced cell death. PMID: 17020792
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亞細胞定位：

Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
蛋白家族：

ERGIC family
數據庫鏈接：

HGNC: 15927

KEGG: hsa:51614

STRING: 9606.ENSP00000349970

UniGene: Hs.472558

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