EPHA10 Antibody, Biotin conjugated
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中文名稱(chēng)：EPHA10兔多克隆抗體, Biotin偶聯(lián)
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貨號(hào)：CSB-PA683366LD01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱(chēng)：Rabbit anti-Homo sapiens (Human) EPHA10 Polyclonal antibody
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Uniprot No.：
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基因名：EPHA10
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別名：Ephrin type-A receptor 10 (EC 2.7.10.1), EPHA10
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Ephrin type-A receptor 10 protein (242-564aa)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Biotin
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克隆類(lèi)型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.
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基因功能參考文獻(xiàn)：
- we defined the novel interaction via expression patterns of EphA10s and EphA10 that promote malignant transformation of breast cancer, and demonstrated the potential benefit in clinical usage. PMID: 28427223
- We have demonstrated the physical association and cellular co-localization of EPHA7 and EPHA10 in breast carcinoma cells. The nuclear co-localization of these two receptors in invasive MDA-MB-231 cells suggests their involvement in transcriptional activation of genes involved in invasiveness. PMID: 27566654
- Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers PMID: 24946238
- Therefore, the idea was conceived that the overexpression of EphA10 in prostate cancers might have a potential as a target for prostate cancer therapy, and formed the basis for the studies reported here. PMID: 24924629
- EphA10 expression at both the gene and protein level in clinical breast cancer tissues is significantly associated with lymph node metastasis as well as stage progression. PMID: 24403271
- EPHA10 does not interact with EPHB6 in breast neoplasms PMID: 21737611
- CLL B-cells showed a more heterogeneous Eph/EFN profile, specially EFNA4, EphB6 and EphA10. PMID: 18819711
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亞細(xì)胞定位：[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
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蛋白家族：Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
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組織特異性：Mainly expressed in testis.
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數(shù)據(jù)庫(kù)鏈接：
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