EMX2 Antibody
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中文名稱：EMX2兔多克隆抗體
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貨號：CSB-PA007657LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: Rat brain tissue, Mouse brain tissue
All lanes: EMX2 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29, 19 kDa
Observed band size: 29 kDa -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA007657LA01HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) EMX2 Polyclonal antibody
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Uniprot No.：
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基因名：EMX2
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別名：Empty spiracles homeobox 2 antibody; Empty spiracles homolog 2 (Drosophila) antibody; Empty spiracles homolog 2 antibody; Empty spiracles like protein 2 antibody; Empty spiracles-like protein 2 antibody; EMX 2 antibody; EMX2 antibody; EMX2_HUMAN antibody; Homeobox protein EMX 2 antibody; Homeobox protein EMX2 antibody
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宿主：Rabbit
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反應種屬：Human, Rat, Mouse
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免疫原：Recombinant Human Homeobox protein EMX2 protein (75-141AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，EMX2 Antibody (CSB-PA007657LA01HU)，的標記方式是Non-conjugated。對于EMX2 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
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基因功能參考文獻：
- EMX2 is frequently down-regulated in human colorectal cancer, and down-regulation of EMX2 is a prognostic marker for disease-free and overall survival. PMID: 28830374
- Emx2 is a novel promising tool for therapy of glioblastoma and prevention of its recurrences. PMID: 27191499
- EMX2 inhibits proliferation and tumorigenesis through inactivation of the Wnt/beta-catenin pathway in CRC cells. PMID: 27712600
- EMX2 expression was down-regulated in lung SCC tissue compared to matched adjacent normal tissue. EMX2 expression was associated with improved overall survival. Knockdown promoted chemo-resistance and cell migration. PMID: 26132438
- Although it is uncommon (0.19%), EMX2 is the first gene identified that if perturbed may cause isolated incomplete mullerian fusion. PMID: 25577462
- Deletions of EMX2 have been associated with a wide range of DSD. PMID: 24975717
- EMX2 expression is downregulated in advanced cases of malignant pleural mesothelioma and may serve as an important prognostic and predictive molecular biomarker of progression-free survival. PMID: 25023662
- downregulation of empty spiracles homeobox 2 (EMX2) was associated with tumor progression and may be a critical factor in the carcinogenesis and progression of endometrial cancer PMID: 23370654
- EMX2 expression led to inhibition of cell proliferation and Wnt signaling pathway both in vitro and in a gastric cancer xenograft model in vivo. PMID: 23029345
- Study analyzed mutations of EMX2 gene in 45 prostate carcinomas, 51 non-small cell lung cancers, 43 gastric carcinomas, 44 colorectal carcinomas, and 43 breast carcinomas by polymerase chain reaction and single-strand conformation polymorphism assay. PMID: 21917011
- Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma. PMID: 21726823
- Data show that human teneurin-1 is directly regulated by EMX2 at a conserved promoter region upstream of the transcription start site, and identify and characterize the EMX2 dependent promoter element of human teneurin-1. PMID: 21651764
- promoter. Restoration of EMX2 expression in lung cancer cells lacking endogenous EMX2 expression suppressed cell proliferation and invasive phenotypes PMID: 20697358
- EMX2 gene has been reported in schezencephaly (cleft brain) including epilepsy in some patients. PMID: 12185771
- In these studies we identify and characterize the regulation of EMX2 by HOXA10. PMID: 12482956
- Endometrial EMX2 expression is aberrant in women with endometriosis and is mediated by altered HOXA10 expression. PMID: 15126568
- EMX2 levels in cortical progenitors of EMX2 transgenic mice disproportionately specify sizes and positions of primary cortical areas. PMID: 15294144
- It is unlikely that the EMX2 or PTEN gene variants investigated contribute to risk for initiation and/or development of endometriosis. PMID: 17563403
- provide results of EMX2 sequencing in 39 new schizencephaly patients, detecting no pathogenic mutations PMID: 18409201
- These data support recent reports that EMX2 but not PAX6 is more directly involved in arealization, highlighting that analysis of human development allows better spatio-temporal resolution than studies in rodents. PMID: 18973570
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相關疾病：Schizencephaly (SCHZC)
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亞細胞定位：Nucleus.
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蛋白家族：EMX homeobox family
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組織特異性：Cerebral cortex.
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數據庫鏈接：
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