EME1 Antibody
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中文名稱：EME1兔多克隆抗體
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貨號：CSB-PA007381
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規格：￥1090
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圖片：
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Western Blot analysis of COLO cells using Eme1 Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：EME1
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別名：6820428D13 antibody; Crossover junction endonuclease EME1 antibody; EC 3.1.22.- antibody; EME1 antibody; Eme1 essential meiotic endonuclease 1 homolog 1 (S. pombe) antibody; EME1; S. pombe; homolog of; 1 antibody; EME1_HUMAN antibody; essential meiotic endonuclease 1 homolog 1 (S pombe) antibody; Essential Meiotic Endonuclease 1 Homolog 1 antibody; essential meiotic endonuclease 1 homolog 2 antibody; Essential meiotic endonuclease 1; S. pombe; homolog of; 1 antibody; FLJ31364 antibody; hMMS4 antibody; homolog of yeast EME1 endonuclease antibody; MGC106543 antibody; MMS4 antibody; MMS4 homolog antibody; MMS4L antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from the Internal region of Human Eme1.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
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基因功能參考文獻：
- The data suggest that subnuclear relocalization is relevant for the function of Mus81-Mms4 complex in response to DNA damage and, probably, of the endonucleases that colocalize with it. PMID: 28813668
- EME-1 deficiency affects cell cycle progression and promotes DNA rereplication. PMID: 16456034
- Low Eme1 levels were more sensitive to the drug than tumors with high levels. PMID: 19267403
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亞細胞定位：Nucleus, nucleolus. Note=Recruited to regions of DNA damage in S-phase cells.
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蛋白家族：EME1/MMS4 family
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數據庫鏈接：
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