EIF2B2 Antibody
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中文名稱：EIF2B2兔多克隆抗體
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貨號：CSB-PA007515GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：EIF2B2
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別名：EI2BB_HUMAN antibody; EIF 2Bbeta antibody; EIF-2Bbeta antibody; EIF2B antibody; EIF2B GDP GTP exchange factor subunit beta antibody; EIF2B2 antibody; EIF2B2 antibody antibody; EIF2BB antibody; Eukaryotic translation initiation factor 2B antibody; Eukaryotic translation initiation factor 2B beta antibody; Eukaryotic translation initiation factor 2B; subunit 2 antibody; Eukaryotic translation initiation factor 2B; subunit 2 beta antibody; Eukaryotic translation initiation factor 2B; subunit 2 beta; 39kDa antibody; S20I15 antibody; S20III15 antibody; Translation initiation factor eIF-2B subunit beta antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human EIF2B2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
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基因功能參考文獻：
- Data show that eIF2Balpha and eIF2Bbeta bind to adjacent surfaces on eIF2alpha-N-terminal domains (NTDs). PMID: 29036434
- It would be better to consider Vanishing White Matter Disease as an eIF2B-related multisystem disorder, not just as a neurological disorder. PMID: 28041799
- An Italian patient is described with a c.638A>G mutation in exon 5 of EIF2B2 gene with very slow progressive vanishing white matter disease. PMID: 22729508
- analysis of vanishing white matter disease caused by EIF2B2 mutation with the presentation of an adrenoleukodystrophy phenotype [case report] PMID: 22285377
- Mutation in EIF2B2 causes childhood ataxia with central nervous system hypomyelination/ vanishing white matter leukodystrophy. PMID: 12707859
- Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B activity. PMID: 14993275
- The role of the residues Ser2 and Ser67 contribute to the important role of the N-terminal region of eIF2beta for its function in mammals. PMID: 16225457
- CACH syndrome is linked to mutations in the five EIF2B--REVIEW PMID: 17878805
- Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to >120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon). PMID: 18263758
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相關(guān)疾病：Leukodystrophy with vanishing white matter (VWM)
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蛋白家族：EIF-2B alpha/beta/delta subunits family
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數(shù)據(jù)庫鏈接：
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