EID3 Antibody
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中文名稱：EID3兔多克隆抗體
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貨號：CSB-PA731077
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA731077(EID3 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA731077(EID3 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：EID3
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別名：E1A-like inhibitor of differentiation 3 antibody; EID 3 antibody; EID-1-like inhibitor of differentiation 3 antibody; EID-3 antibody; EID3 antibody; EID3_HUMAN antibody; EP300 interacting inhibitor of differentiation 3 antibody; EP300-interacting inhibitor of differentiation 3 antibody; FLJ25832 antibody; Non-SMC element 4; S. cerevisiae; homolog of; B antibody; Non-structural maintenance of chromosomes element 4 homolog B antibody; NSE4B antibody; NSMCE4B antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthetic peptide of Human EID3
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.; Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors.
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基因功能參考文獻：
- Knockdown of EID3 by specific shRNA attenuated BMS-345541 -induced radiosensitization in MCF-7 cells. PMID: 30114644
- These findings indicated a novel mechanism by which EID3, a p300 acetyltransferase inhibitor, could directly affect DNMT3A, this enzyme possesses dual methylation and demethylation abilities. PMID: 28074931
- EID3 acts as an inhibitor of CBP/p300-dependent transcription in a tissue-specific manner. PMID: 15987788
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亞細胞定位：Nucleus. Cytoplasm. Chromosome, telomere.
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蛋白家族：NSE4 family
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組織特異性：Highly expressed in testis.
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數據庫鏈接：
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