EHD4 Antibody

說明書

產品詳情

Uniprot No.：

Q9H223
基因名：

EHD4
別名：

EHD4 antibody; HCA10 antibody; HCA11 antibody; PAST4 antibody; FKSG7EH domain-containing protein 4 antibody; Hepatocellular carcinoma-associated protein 10/11 antibody; PAST homolog 4 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human EHD4
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport.
基因功能參考文獻：
1. Ezrin and EHD4 appear to be involved in the ability of Nef to increase hiv-1 virus infectivity. PMID: 23325686
2. Retrograde signaling through Pincher-generated Trk-multivesicular bodies is distinctively refractory to signal termination by lysosomal processing PMID: 21187387
3. EHD4 is involved in the control of trafficking at the early endosome and regulates exit of cargo toward both the recycling compartment and the late endocytic pathway. PMID: 18331452
亞細胞定位：

Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
蛋白家族：

TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family, EHD subfamily
組織特異性：

Highly expressed in pancreas and heart.
數據庫鏈接：

HGNC: 3245

OMIM: 605892

KEGG: hsa:30844

STRING: 9606.ENSP00000220325

UniGene: Hs.143703

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