DYNC1I1 Antibody
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中文名稱：DYNC1I1兔多克隆抗體
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貨號：CSB-PA007293GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：DYNC1I1
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別名：Cytoplasmic dynein 1 intermediate chain 1 antibody; Cytoplasmic dynein intermediate chain 1 antibody; cytosolic antibody; DC1I1_HUMAN antibody; DH IC 1 antibody; DH IC-1 antibody; DH IC1 antibody; DNCI1 antibody; DNCIC1 antibody; Dync1i1 antibody; Dynein cytoplasmic 1 intermediate chain 1 antibody; Dynein intermediate chain 1 antibody; Dynein intermediate chain 1; cytosolic antibody; Dynein; cytoplasmic; intermediate polypeptide 1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human DYNC1I1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
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基因功能參考文獻：
- SQSTM1 is required for proper dynein motility and trafficking along microtubules. PMID: 25015291
- Deletions of the exons with regulatory potential of DYNC1I1 are an example of the emerging role of exonic enhancer elements and their implications in congenital malformation syndromes PMID: 25231166
- NCAM and dynein have roles in tethering dynamic microtubules and maintaining synaptic density in cortical neurons PMID: 23960070
- Both P-TEFb recruitment to the HIV long terminal repeat and enhanced HIV processivity were blocked by ERK inhibitor, but not by AKT and PI3K inhibitors. PMID: 21763495
- the mRNA expression level of DYNC1I1 were significantly up-regulated in tumorous liver tissues compared with corresponding nontumorous counterparts. PMID: 21767414
- NDE1 and NDEL1 act upstream of LIS1 in dynein recruitment, and/or activation, on the membrane. PMID: 20048338
- identification of a novel 24-kDa protein that binds directly to dynein intermediate chain [PLAC-24] PMID: 12006665
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亞細胞定位：Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
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蛋白家族：Dynein intermediate chain family
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數據庫鏈接：
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