DUSP26 Antibody

中文名稱：

DUSP26兔多克隆抗體
貨號：

CSB-PA863128LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA863128LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA863128LA01HU at dilution of 1:100

Immunofluorescence staining of SH-SY5Y cells with CSB-PA863128LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DUSP26 Polyclonal antibody
Uniprot No.：

Q9BV47
基因名：

DUSP26
別名：

DSP-4 antibody; Dual specificity phosphatase 26 (putative) antibody; Dual specificity phosphatase 26 antibody; Dual specificity phosphatase SKRP3 antibody; Dual specificity protein phosphatase 26 antibody; DUS26_HUMAN antibody; DUSP24 antibody; DUSP26 antibody; Hypothetical protein FLJ31142 antibody; LDP 4 antibody; LDP-4 antibody; Low molecular mass dual specificity phosphatase 4 antibody; Low-molecular-mass dual-specificity phosphatase 4 antibody; MAP kinase phosphatase 8 antibody; MGC1136 antibody; MGC2627 antibody; Mitogen activated protein kinase phosphatase 8 antibody; Mitogen-activated protein kinase phosphatase 8 antibody; MKP-8 antibody; MKP8 antibody; NATA1 antibody; NATA1 protein antibody; Novel amplified gene in thyroid anaplastic cancer antibody; SKRP3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Dual specificity protein phosphatase 26 protein (1-211AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，DUSP26 Antibody (CSB-PA863128LA01HU)，的標記方式是Non-conjugated。對于DUSP26 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA863128LB01HU	DUSP26 Antibody, HRP conjugated	ELISA
FITC	CSB-PA863128LC01HU	DUSP26 Antibody, FITC conjugated
Biotin	CSB-PA863128LD01HU	DUSP26 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
基因功能參考文獻：
1. Enhanced expression of DUSP26 was observed in the hippocampus of Alzheimer's disease patients. PMID: 26924229
2. results suggest that AK2 is an associated activator of DUSP26 and suppresses cell proliferation by FADD dephosphorylation, postulating AK2 as a negative regulator of tumour growth. PMID: 24548998
3. The study reports the 1.68 A crystal structure of a catalytically inactive mutant (Cys152Ser) of DUSP26 lacking the first 60 N-terminal residues (DeltaN60-C/S-DUSP26). PMID: 23298255
4. DUSP26 may function as a tumour suppressor in particular cancers. PMID: 20347885
5. DUSP26 functions as a p53 phosphatase PMID: 20562916
6. DUSP26 effectively dephosphorylates p38 and has a little effect on extracellular signal-regulated kinase in anaplastic thyroid cancer. PMID: 16924234
7. Downregulation of Dusp26 may contribute to malignant phenotypes of glioma. PMID: 19043453
顯示更多

收起更多
亞細胞定位：

Cytoplasm. Nucleus. Golgi apparatus.
蛋白家族：

Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
組織特異性：

Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.
數據庫鏈接：

HGNC: 28161

KEGG: hsa:78986

STRING: 9606.ENSP00000256261

UniGene: Hs.8719

Most popular with customers

YWHAG Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
YWHAB Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF, FC

Species Reactivity: Human, Mouse, Rat
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
XRCC5 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF

Species Reactivity: Human
XPNPEP1 Recombinant Monoclonal Antibody

Applications: ELISA, IHC, FC

Species Reactivity: Human
WT1 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WFDC2 Recombinant Monoclonal Antibody

Applications: ELISA, WB, FC

Species Reactivity: Human
WDR5 Recombinant Monoclonal Antibody

Applications: ELISA, IHC, FC

Species Reactivity: Human