DTNB Antibody
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中文名稱：DTNB兔多克隆抗體
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貨號：CSB-PA187891
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規格：￥1100
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圖片：
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 823 cells, Primary antibody: CSB-PA187891(DTNB Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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其他：
產品詳情
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Uniprot No.：
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基因名：DTNB
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別名：Beta dystrobrevin antibody; Beta-dystrobrevin antibody; DTN B antibody; DTN-B antibody; Dtnb antibody; DTNB_HUMAN antibody; Dystrobrevin beta antibody; MGC17163 antibody; MGC57126 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Fusion protein of Human DTNB
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids. May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation. May be required for proper maturation and function of a subset of inhibitory synapses.
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基因功能參考文獻：
- Data provide new insights into the role of beta-dystrobrevin in the molecular mechanisms underlying neuronal differentiation that could be relevant in the establishment of the cognitive impairment in Duchene muscular dystrophy. PMID: 27223470
- beta-dystrobrevin interacts with the HMG20 proteins iBRAF and BRAF35 PMID: 20530487
- results suggest that dysbindin assembled into BLOC-1 is not a physiological binding partner of the dystrobrevins, likely due to engagement of its dystrobrevin-binding region in interactions with other subunits PMID: 16448387
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亞細胞定位：Cytoplasm. Cell junction, synapse, postsynaptic density. Cell projection, dendrite. Basal cell membrane. Cell junction, synapse, postsynapse. Nucleus.
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蛋白家族：Dystrophin family, Dystrobrevin subfamily
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組織特異性：Highly expressed in brain, kidney and pancreas.
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數據庫鏈接：
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