DTD1 Antibody
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中文名稱：DTD1兔多克隆抗體
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貨號：CSB-PA007214GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：DTD1
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別名：bA379J5.3 antibody; bA555E18.1 antibody; C20orf88 antibody; D tyrosyl tRNA deacylase 1 homolog antibody; D-tyrosyl-tRNA(Tyr) deacylase 1 antibody; DNA unwinding element binding protein antibody; DTD1 antibody; DTD1_HUMAN antibody; DUE B antibody; DUEB antibody; HARS2 antibody; Histidyl tRNA synthetase 2 antibody; Histidyl-tRNA synthase-related antibody; MGC119131 antibody; MGC41905 antibody; pqn 68 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human DTD1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Possible ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes.; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
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基因功能參考文獻：
- The state of DUE-B phosphorylation is maintained by the equilibrium between Cdc7-dependent phosphorylation and PP2A-dependent dephosphorylation. PMID: 25258324
- LDI-PCR revealed a fusion between DTD1 exon 4 and PDGFRB exon 12 in the cases with t(5;14)(q33;q32) and t(5;20)(q33;p11). PMID: 24772479
- DTD1 variants do not affect the abnormalities of the upper airways in aspirin-intolerant asthma patients PMID: 21479357
- The coordinated binding of DUE-B and Cdc45 to origins and the physical interactions of DUE-B, Cdc45, and TopBP1 suggest that complexes of these proteins are necessary for replication initiation. PMID: 20065034
- cloning and identification of novel cDNA which may be associated with FKBP25 PMID: 12392168
- DUE-B, a c-myc DNA-unwinding element-binding protein, plays an important role in replication in vivo. PMID: 15653697
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亞細胞定位：Nucleus. Cytoplasm. Note=Associated with chromatin at some replication origins containing functional DNA-unwinding elements (PubMed:20065034).
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蛋白家族：DTD family
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組織特異性：Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain.
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數據庫鏈接：
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