DPEP1 Antibody
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中文名稱：DPEP1兔多克隆抗體
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貨號：CSB-PA007123LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: HT-29 whole cell lysate, A549 whole cell lysate, U87 whole cell lysate, Hela whole cell lysate
All lanes: DPEP1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa -
Immunofluorescence staining of HepG2 cells with CSB-PA007123LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) DPEP1 Polyclonal antibody
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Uniprot No.：
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基因名：DPEP1
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別名：Dehydropeptidase-I antibody; Dipeptidase 1 (renal) antibody; Dipeptidase 1 antibody; DPEP1 antibody; DPEP1_HUMAN antibody; hRDP antibody; MBD1 antibody; MDP antibody; Microsomal dipeptidase antibody; RDP antibody; Renal dipeptidase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Dipeptidase 1 protein (23-252AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，DPEP1 Antibody (CSB-PA007123LA01HU)，的標記方式是Non-conjugated。對于DPEP1 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Antigen Affinity purified & Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Possesses also beta lactamase activity and hydrolytically inactivates beta-lactam antibiotics.; Independently of its dipeptidase activity acts as an adhesion receptor for neutrophils recruitement from bloodstream into inflammed lungs and liver.
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基因功能參考文獻：
- The results suggest that DPEP1 promotes cancer metastasis by regulating E-cadherin plasticity and that it might be a potential therapeutic target for preventing the progression of colon cancer. PMID: 26824987
- In this study, we present an analysis of Neanderthal introgression at the dipeptidase 1 gene, DPEP1. PMID: 26392408
- Dipeptidase 1 has been identified as an excellent marker of high-grade IEN and CRC, and may thus be applied for screening of early neoplastic lesions and for prognostic stratification. PMID: 23839495
- DPEP1 plays a role in pancreatic cancer aggressiveness. PMID: 22363658
- DPEP1 is expressed in the early stages of colon carcinogenesis and affects cancer cell invasiveness. PMID: 20824289
- we identified a novel immunohistochemical marker, dipeptidase 1, to distinguish primary mucinous ovarian cancers from ovarian metastasis of colorectal cancers. PMID: 21076463
- Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis PMID: 12144777
- DPEP1 has a role in colorectal carcinoma PMID: 15145522
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亞細胞定位：Apical cell membrane; Lipid-anchor, GPI-anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI-anchor.
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蛋白家族：Metallo-dependent hydrolases superfamily, Peptidase M19 family
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組織特異性：Expressed in lung and kidneys.
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數據庫鏈接：
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