DNER Antibody
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中文名稱：DNER兔多克隆抗體
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貨號：CSB-PA818784NA01HU
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規格：￥440
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圖片：
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Immunofluorescence staining of U87 cells with CSB-PA818784NA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) DNER Polyclonal antibody
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Uniprot No.：
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基因名：DNER
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別名：bet antibody; Brain EGF repeat-containing transmembrane protein antibody; Bret antibody; Delta and Notch-like epidermal growth factor-related receptor antibody; Delta notch like EGF repeat containing transmembrane antibody; Delta/notch like EGF repeat containing antibody; Delta/notch-like EGF-related receptor antibody; Dner antibody; DNER_HUMAN antibody; PRO299 antibody; Transmembrane protein Bet antibody; UNQ26 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Peptide sequence from Human Delta and Notch-like epidermal growth factor-related receptor protein (150-168AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，DNER Antibody (CSB-PA818784NA01HU)，的標記方式是Non-conjugated。對于DNER Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, IF
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推薦稀釋比：
Application Recommended Dilution IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
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基因功能參考文獻：
- quantum dot-based immunofluorescent imaging and quantitative analytical system (QD-IIQAS) is an easy and accurate method for assessing DNER and the DNER expression was an independent prognostic factor in prostate cancer. PMID: 29843212
- Collectively, our study identified an unexpected transcriptional repression function of the BET bromodomain and a novel mechanism for TAZ upregulation. PMID: 27717711
- our findings show that targeting BET proteins for degradation represents an effective therapeutic strategy for Triple-negative breast cancers (TNBC)treatment PMID: 28209615
- is not a Notch ligand PMID: 27622512
- we review and discuss the structural biology of BET family BDs and their applications in major diseases. PMID: 27240990
- DNER rs1861612 C to T change and variant T genotype may contribute to T2DM in a Chinese Han population PMID: 25300688
- These studies implicate DNER as a susceptibility gene for T2DM in American Indians. PMID: 24101674
- Our data suggest that clathrin-independent endocytosis is critical for the polarized targeting of somatodendritic proteins(DNER). PMID: 20367751
- The inhibition of DNER protein resulted in an increase in adipocyte maturation, partly via a reduction of cell proliferation through elevation of CCAAT-Enhancer-Binding Protein-delta expression. PMID: 20070733
- expression in developing and mature central nervous system PMID: 11950833
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亞細胞定位：Cell membrane; Single-pass type I membrane protein.
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組織特異性：Expressed in brain, spinal cord and adrenal gland.
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數據庫鏈接：
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