DNAJC19 Antibody
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中文名稱：DNAJC19兔多克隆抗體
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貨號：CSB-PA007026GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：DnaJ (Hsp40) homolog; subfamily C; member 19 antibody; DnaJ homolog subfamily C member 19 antibody; DNAJC19 antibody; homolog of yeast TIM14 antibody; Mitochondrial import inner membrane translocase subunit TIM14 antibody; PAM18 antibody; TIM 14 antibody; TIM14 antibody; TIM14_HUMAN antibody; TIMM 14 antibody; TIMM14 antibody; translocase of the inner mitochondrial membrane 14 antibody; Translocase of the inner mitochondrial membrane 14; yeast homolog of antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human DNAJC19
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity.
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基因功能參考文獻：
- Both DnaJC15 and DnaJC19 formed two distinct subcomplexes with Magmas at the import channel. PMID: 27330077
- The loss of DNAJC19/PHB complexes affects cardiolipin acylation and leads to the accumulation of cardiolipin species with altered acyl chains. PMID: 24856930
- A report of a new mutation in the human DNAJC19 gene that causes early onset dilated cardiomyopathy syndrome in two brothers of Finnish origin. PMID: 22797137
- The association of dilated cardiomyopathy with ataxia (DCMA) syndrome with a segment of 3q26.33 and the identification of a splice mutation in a novel gene DNAJC19 in DCMA patients. PMID: 16055927
- Dilated cardiomyopathy caused by homozygous mutations in a novel gene, DNAJC19, presumed to play a role in importation of mitochondrial proteins. PMID: 17244376
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相關疾病：3-methylglutaconic aciduria 5 (MGA5)
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亞細胞定位：Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
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蛋白家族：TIM14 family
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組織特異性：Ubiquitously expressed.
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數據庫鏈接：
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