DNAJB4 Antibody

中文名稱：

DNAJB4兔多克隆抗體
貨號：

CSB-PA10929A0Rb
規格：

￥440
圖片：
Western blot
All lanes: DNAJB4 antibody at 2µg/ml
Lane 1: Hela whole cell lysate
Lane 2: Mouse heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 38 kDa
Observed band size: 38 kDa

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA10929A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA10929A0Rb at dilution of 1:100
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DNAJB4 Polyclonal antibody
Uniprot No.：

Q9UDY4
基因名：

DNAJB4
別名：

DjB4 antibody; DnaJ (Hsp40) homolog subfamily B member 4 antibody; DnaJ homolog subfamily B member 4 antibody; DnaJ like heat shock protein 40 antibody; DNAJB 4 antibody; DNAJB4 antibody; DNAJW antibody; DNJB4_HUMAN antibody; Heat shock 40 kDa protein 1 homolog antibody; Heat shock protein 40 homolog antibody; HLJ 1 antibody; HLJ1 antibody; HSP40 homolog antibody; Human liver DnaJ-like protein antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human DnaJ homolog subfamily B member 4 protein (1-337AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，DNAJB4 Antibody (CSB-PA10929A0Rb)，的標記方式是Non-conjugated。對于DNAJB4 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA10929B0Rb	DNAJB4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA10929C0Rb	DNAJB4 Antibody, FITC conjugated
Biotin	CSB-PA10929D0Rb	DNAJB4 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
基因功能參考文獻：
1. These new observations support the idea that HLJ1 is a tumor suppressor candidate and potential biomarker for breast cancer PMID: 28481734
2. HLJ1 is an endogenous Src inhibitor that can suppress cancer metastasis through complex interacting mechanisms. PMID: 27065329
3. HLJ1 is a strong tumor suppressor for colorectal carcinoma PMID: 24696714
4. Low expression of DNAJB4 is associated with gastric carcinomas. PMID: 24293545
5. Silencing of HLJ1 partially reverses the inhibition of cancer-cell invasion by andrographolide. PMID: 23306212
6. HBV could promote HLJ1 expression by up-regulating the transcription factor YY1. PMID: 21345358
7. acidic stress increases the association between HLJ1 and beta-actin to modulate migration of human lung cancer cells PMID: 20615403
8. HLJ1 switches the role of NPM1, which can act as tumor suppressor or oncogene, by modulating the oligomerization of NPM1 via HLJ1-NPM1 heterodimer formation and recruiting AP-2alpha to the MMP-2 promoter. PMID: 20145123
9. Results indicate that DjA1 and DjB4 of subfamilies A and B of human Hsp40 have different quaternary structures and chaperone functions. PMID: 15661747
10. The increase in HLJ1 and E-cadherin expression, as well as the suppression of invasion ability, can be reversed specifically by HLJ1 siRNA. PMID: 15782117
11. HLJ1 is a novel tumor suppressor in NSCLC, and high HLJ1 expression is associated with reduced cancer recurrence and prolonged survival of NSCLC patients. PMID: 16788156
12. Results show that curcumin induces HLJ1, through activation of the JNK/JunD pathway, and inhibits lung cancer cell invasion and metastasis by modulating E-cadherin expression. PMID: 18794131
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亞細胞定位：

Cytoplasm. Cell membrane. Note=Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.
組織特異性：

Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.
數據庫鏈接：

HGNC: 14886

OMIM: 611327

KEGG: hsa:11080

STRING: 9606.ENSP00000359799

UniGene: Hs.13852

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