DIMT1 Antibody
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中文名稱：DIMT1兔多克隆抗體
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貨號：CSB-PA892161LA01HU
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規格：￥440
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圖片：
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Western blot
All lanes: DIMT1 antibody at 2μg/ml + Mouse thymus tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 35 kDa
Observed band size: 35 kDa -
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA892161LA01HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA892161LA01HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) DIMT1 Polyclonal antibody
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Uniprot No.：
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基因名：DIMT1
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別名：18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase antibody; 18S rRNA dimethylase antibody; DIM1 antibody; DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) antibody; DIM1 dimethyladenosine transferase 1 homolog antibody; DIM1 dimethyladenosine transferase 1 like antibody; DIM1 dimethyladenosine transferase 1-like antibody; Dimethyladenosine transferase antibody; DIMT1 antibody; DIMT1_HUMAN antibody; DIMT1L antibody; HSA9761 antibody; HUSSY5 antibody; N''-adenosyl(rRNA) dimethyltransferase antibody; Probable 18S rRNA (adenine(1779) N(6)/adenine(1780) N(6)) dimethyltransferase antibody; Probable 18S rRNA dimethylase antibody; Probable dimethyladenosine transferase antibody; Probable S adenosylmethionine 6 N',N' adenosyl(rRNA) dimethyltransferase antibody; S adenosylmethionine 6 N',N' adenosyl(rRNA) dimethyltransferase antibody; S-adenosylmethionine-6-N'' antibody
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宿主：Rabbit
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反應種屬：Human, Mouse
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免疫原：Recombinant Human Probable dimethyladenosine transferase protein (1-313AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，DIMT1 Antibody (CSB-PA892161LA01HU)，的標記方式是Non-conjugated。對于DIMT1 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity.
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基因功能參考文獻：
- DIMT1 is overexpressed in gastric carcinoma and is significantly correlated with poor prognosis. PMID: 28601661
- Studies show that miroRNA miR-210 acts as a tumor suppressor in hypoxic conditions by downregulating the 18S rRNA base methyltransferase (DIMT1)-interferon regulatory factor 4 (IRF4) axis. PMID: 28164410
- DIMT1L and WBSCR22-TRMT112 are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity. PMID: 25851604
- Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection by activating STMN1 and DIMT1. PMID: 25187177
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亞細胞定位：Nucleus, nucleoplasm. Nucleus, nucleolus.
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蛋白家族：Class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family
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數據庫鏈接：
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