DHX32 Antibody
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中文名稱：DHX32兔多克隆抗體
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貨號：CSB-PA006874GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：DHX32
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別名：3110079L04Rik antibody; AA408140 antibody; Ddx32 antibody; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 antibody; DEAD/H box 32 antibody; DEAD/H helicase like protein 1 antibody; DEAD/H helicase-like protein 1 antibody; DEAH (Asp-Glu-Ala-His) box polypeptide 32 antibody; DEAH box protein 32 antibody; DHLP1 antibody; DHX32 antibody; DHX32_HUMAN antibody; Helicase DDX32 antibody; HuDDX32 antibody; Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human DHX32
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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基因功能參考文獻(xiàn)：
- DHX32 is an upstream regulator for beta-catenin, which promotes the activity of beta-catenin to upregulate expression of VEGFA in colorectal cancer cells. Depletion of DHX32 expression suppressed colorectal cancer tumor angiogenesis and tumor growth. PMID: 28330603
- Structural characterization and expression of the DDX32 gene. Expression studies show that DDX32 is widespread but specifically down-regulated in acute lymphoblastic leukemias and might play a role in normal and/or abnormal lymphopoiesis. PMID: 12163057
- cloned DHX32 proximal promoter and identified a 218bp fragment containing two potential binding sites for the transcription factor nuclear factor of activated T cells (NF-AT) PMID: 16414036
- These results suggest that DHX32 is a putative RNA helicase that might be involved in regulating nuclear and mitochondrial gene expression. PMID: 16959245
- dysregulated expression of DHX32 might lead to as of yet unknown changes in mitochondrial homeostasis manifested by cytoplasmic redistribution of the molecular chaperon Hsp60 PMID: 17174952
- In peripheral blood lymphocytes, a correlation between DHX32 and c-FLIP short expression was detected in response to different T-cell activation stimuli. Results suggest DHX32 involvement in regulating T-cell response to apoptotic stimuli. PMID: 17352256
- DHX32 may play an important role in the development of colorectal cancer and could serve as a novel biomarker for colorectal cancer after additional investigation. PMID: 19161603
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亞細(xì)胞定位：Nucleus. Mitochondrion.
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蛋白家族：DEAD box helicase family, DEAH subfamily
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組織特異性：Expressed in lymphoid tissues (at protein level). Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung, lymphoid tissues and blood leukocytes.
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數(shù)據(jù)庫鏈接：
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