DECR1 Antibody
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中文名稱：DECR1兔多克隆抗體
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貨號：CSB-PA087606
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA087606(DECR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA087606(DECR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) -
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Human endometrial carcinoma tissue, Human colon cancer tissue, human fetal liver tissue, PC3 cells, Primary antibody: CSB-PA087606(DECR1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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其他：
產品詳情
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Uniprot No.：
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基因名：DECR1
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別名：1200012F07Rik antibody; 2 antibody; 2,4 dienoyl CoA reductase [NADPH] antibody; 2,4 dienoyl CoA reductase 1 antibody; 2,4 dienoyl CoA reductase mitochondrial antibody; 2,4-dienoyl-CoA reductase; mitochondrial antibody; 4 enoyl CoA reductase antibody; 4-dienoyl-CoA reductase [NADPH] antibody; 4-enoyl-CoA reductase [NADPH] antibody; DECR 1 antibody; DECR antibody; DECR_HUMAN antibody; DECR1 antibody; Nadph antibody; OTTMUSP00000004962 antibody; RP23-338J24.3 antibody; SDR18C1 antibody; Short chain dehydrogenase/reductase family 18C member 1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic peptide of Human DECR1
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:500-1:2000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
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基因功能參考文獻：
- Our study is the first to demonstrate the novel function of UA in NET formation and may provide insight into the management of patients with hyperuricemia. PMID: 24326071
- Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase PMID: 15531764
- Sequence alignment indicates that there are five highly conserved acidic residues, one of which (E276) might act as a proton donor. PMID: 15629123
- mutational defects cause chronic granulomatous disease in humans PMID: 18193341
- The luminal NADPH pool is an important antiapoptotic factor in neutrophil granulocytes. PMID: 18472006
- The TT genotype of C677T polymorphism in the MTHFR gene contributes to genetic susceptibility of acute ischemic stroke in a Singapore population. PMID: 19049547
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相關疾病：2,4-dienoyl-CoA reductase deficiency (DECRD)
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亞細胞定位：Mitochondrion.
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蛋白家族：Short-chain dehydrogenases/reductases (SDR) family, 2,4-dienoyl-CoA reductase subfamily
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組織特異性：Heart = liver = pancreas > kidney >> skeletal muscle = lung.
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數據庫鏈接：
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