DDX25 Antibody
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中文名稱：DDX25兔多克隆抗體
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貨號：CSB-PA006615GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：DDX25
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別名：DDX25 antibody; GRTHATP-dependent RNA helicase DDX25 antibody; EC 3.6.4.13 antibody; DEAD box protein 25 antibody; Gonadotropin-regulated testicular RNA helicase antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human DDX25
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development.
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基因功能參考文獻：
- Analysed the association of GRTH gene IVS6+55G/T and c.852C/T polymorphisms with male infertility. The c.852 T allele was associated with an increased risk of male infertility (OR: 3.16, P = 0.008), whereas IVS6+55G/T allele conferred no risk. PMID: 24168058
- multifunctional RNA helicase that is an essential regulator of spermatogenesis PMID: 19875492
- SNP IVS6+55G-->T and c.852C-->T of GRTH gene may be associated with male infertility with azoospermia or severe oligozoospermia. PMID: 16293649
- Data show that the Arg(242)His missense mutation of the GRTH/DDX25 gene associated with expression of a protein with reduced basicity, and the absence of the phospho-GRTH species, could impact on germ cell development and/or function. PMID: 17848414
- The association of GRTH mutations with male infertility underlines the importance of GRTH as a central, post-transcriptional regulator of spermatogenesis. PMID: 17889551
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亞細胞定位：Cytoplasm. Nucleus.
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蛋白家族：DEAD box helicase family
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組織特異性：Highly expressed in the Leydig and germ cells of the testis and weakly expressed in the pituitary and hypothalamus.
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數據庫鏈接：
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